Results 91 to 100 of about 3,358,332 (268)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Improved Coverage of Massive MIMO HetNets Modeled Using Stochastic Geometry Techniques

open access: yesIEEE Open Journal of Vehicular Technology
Most current stochastic geometric modeling of heterogeneous cellular networks (HetNets) assumes independent deployment of small-cell base stations (SBSs) with respect to macrocell base stations (MBSs), which leads to limited enhancement in network ...
Bitan Banerjee   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Connecting communities: Enhancing broadband access in rural Tanzania through small cell deployment

open access: yesJournal of Engineering Research and Reviews
Aim: The aim of this study is to explore potential performance enhancement to a network infrastructure comprising with Macro-cells only by introducing and deploying cost-effective and adaptable small-cell backhaul connections.
Pascal Yamakili   +1 more
doaj   +1 more source

Whole-Genome Resequencing of Red Junglefowl and Indigenous Village Chicken Reveal New Insights on the Genome Dynamics of the Species

open access: yesFrontiers in Genetics, 2018
The red junglefowl Gallus gallus is the main progenitor of domestic chicken, the commonest livestock species, outnumbering humans by an approximate ratio of six to one.
Raman A. Lawal   +7 more
doaj   +1 more source

Analysis of Molecular Biomarkers in Resected Early-Stage Non-Small Cells Lung Cancer: A Narrative Review. [PDF]

open access: yesCancers (Basel), 2022
Gallina FT   +13 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy