Recognition of Small Surface Fatigue Crack Initiation and Crack Tip.
ISHII, Akira +3 more
openaire +2 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Magneto-Mechanical Coupling Modeling and Full-Cycle Characterization of V-Shaped Crack Evolution in Q345 Steel Using Metal Magnetic Memory. [PDF]
Xu C, Xing H, Zhao L, Miu H, Zhang H.
europepmc +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Concrete Crack Detection and Classification Methods Based on Machine Vision and Deep Learning. [PDF]
Chen W +7 more
europepmc +1 more source
Crack identification based on natural frequency of cracked small pipes [PDF]
Zhongqiang Zhang +2 more
openaire +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Predictions of Crack Growth Rates, R-Ratio and Overload Effects Based on Smooth Specimen LCF Data and the Moving Plastic Stress Field Ahead of the Crack Tip. [PDF]
Williams S, Whittaker M, Hardy M.
europepmc +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Investigation on the Effect of Combined Addition of CNTs and La<sub>2</sub>O<sub>3</sub> on the Microstructure and Properties of W<sub>2</sub>CoB<sub>2</sub> Cermet. [PDF]
Zhu X, Qu F, Pan Y, Ke D, Liu L.
europepmc +1 more source

