Results 71 to 80 of about 6,061,888 (289)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

MFIA-YOLO: A Small-Object Defect Detection Model for Transmission Line Spacers

Energies
UAV inspection images of transmission line spacers often contain small-scale defect targets, complex backgrounds, and weak fine-grained features. We propose MFIA-YOLO, a small-object defect detection model for spacer defects.
Jinlong Du, Xiangyu Wang, Haiyang Lu, Xiaoye Zhang, Quanlei Cui, Tong Zhang, Zhongyu Wei, Yujian Ding   +7 more
doaj   +1 more source

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis. [PDF]

PLoS ONE, 2015
Bipotent axial stem cells residing in the caudal epiblast during late gastrulation generate neuroectodermal and presomitic mesodermal progeny that coordinate somitogenesis with neural tube formation, but the mechanism that controls these two fates is not
Thomas J Cunningham, Thomas Brade, Lisa L Sandell, Mark Lewandoski, Paul A Trainor, Alexandre Colas, Mark Mercola, Gregg Duester   +7 more
doaj   +1 more source

Small Bone Defects Augmentation

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2014
The aim of the study was to compare different techniques for small alveolar crest bone defect augmentation with implants adapted to these bone defects. Platform switching , machined collar and zirconia collar implants were placed in the upper and lower jaw in two patients.
Criatian RATIU, Simona CAVALU, Adina Bianca BOŞCA, Flavia RUXANDA, Vasile RUS, Viorel MICLAUS   +5 more
openaire   +2 more sources

Small

, 2014
A proverbial objective in nanomaterial science is to construct low-dimensional nanoparticle (NP) assemblies with fascinating properties, which have shown great promise in optical, electronic and biomedical applications.
Yue, Hua, Li, Wenjing, Li, Weizhen, Zhang, Wei, Wei, Wei, Tang, Pei, Lin, Lili, Ma, Ding, Fu, Qiang, Ma, Guanghui, Yin, Zhen   +10 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Classification of binary systematic codes of small defect

Le Matematiche, 2014
In this paper non-trivial non-linear binary systematic AMDS codes are classified in terms of their  weight distributions, employing only elementary techniques.
Alberto Ravagnani
doaj  

Reconstruction of Small Soft Tissue Nasal Defects [PDF]

Seminars in Plastic Surgery, 2013
Nasal defect repair has been one of the more challenging areas of reconstructive surgery due to the lack of uniform nasal skin thickness and complex contours. Currently, algorithms for medium to large nasal soft tissue defects have been well defined by various authors.
Erik M, Wolfswinkel, William M, Weathers, David, Cheng, James F, Thornton   +3 more
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source