Results 111 to 120 of about 510,839 (268)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

EBBA-detector: An effective detector for defect detection in solar panel EL images with unbalanced data.

PLoS ONE
Solar panel defect detection, a crucial quality control task in the manufacturing process, often faces challenges such as varying defect sizes, severe image background interference, and imbalanced data sample distribution.
Yixing Zhang, Ziyan Mo, Zhuan Xin, Xianyu Chen, Yuqin Deng, Xuan Dong   +5 more
doaj   +1 more source

IM-DETR: DETR with Mix-Encoder for Industrial Scenarios

Applied Sciences
Industrial defect detection is a fundamental task in intelligent manufacturing, yet existing object detection methods often struggle with the characteristics of industrial defects, such as small size, irregular shapes, and complex visual backgrounds ...
Shiyou Liu, Yong Feng, Dongzi Wang, Zijie Zhou, Haibing Wang, Jinsong Wu, Xiangdong Wang, Xuekai Wei, Jielu Yan, Weizhi Xian, Yi Qin   +10 more
doaj   +1 more source

Classification of binary systematic codes of small defect

CoRR, 2012
Le Matematiche (to appear)
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

A two-stage defect detection method for unevenly illuminated self-adhesive printed materials

Scientific Reports
The process of printing defect detection usually suffers from challenges such as inaccurate defect extraction and localization, caused by uneven illumination and complex textures.
Guifeng Peng, Tao Song, Songxiao Cao, Bin Zhou, Qing Jiang   +4 more
doaj   +1 more source

A “Small” Defect With Malignant Effect

Journal of the American College of Cardiology, 2011
Hammerstingl, Christoph, Nickenig, Georg, Weber, Stefan, Knuefermann, Pascal   +3 more
openaire   +2 more sources