Results 31 to 40 of about 5,776,434 (207)

Enterovesical Herniation: A Rare Complication After Transurethral Resection of Bladder Tumor

Journal of Urological Surgery, 2019
Enterovesical herniation through an acquired bladder wall defect after transurethral resection is an exceedingly rare complication. Small bladder perforations may go unrecognized after transurethral resection as adherent bowel loops seal the defect.
Kanishka Samanta, Pramod Kumar Sharma, Souvik Chatterjee, Dilip Karmakar   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

PDDD-Net: Defect Detection Network Based on Parallel Attention Mechanism and Dual-Channel Spatial Pyramid Pooling

IEEE Access, 2023
Owing to the small size of the defect pixel area and poor defect-background contrast issues in industrial images, noise and missed detection can easily occur. Therefore, automated defect detection is both necessary and challenging.
Tingting Sui, Junwen Wang
doaj   +1 more source

Highly-Sensitive and Frequency-Selective Imaging of Defects via Local Defect Resonance [PDF]

, 2014
In this paper, a consistent way to enhance acoustic, optical and thermal defect responses is suggested by using selective ultrasonic activation of defects based on the concept of local defect resonance (LDR).
Solodov Igor, Gulnizkij Nikolay, Rahammer Markus   +2 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Detection method of small size defects on pipeline weld surface based on improved YOLOv7.

PLoS ONE
The background of pipeline weld surface defect image is complex, and the defect size is small. Aiming at the small defect size in the weld image, which is easy to cause missed detection and false detection, a lightweight target detection algorithm based ...
Xiangqian Xu, Wenting Hou, Xing Li
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Enhancing grid reliability through advanced insulator defect identification.

PLoS ONE
The article presents an innovative approach for detecting defects in insulators used in high-voltage power transmission lines, employing an enhanced Detection Transformer (DETR) model, termed IF-DETR.
Xiao Wang, Ting Yang, Yuntao Zou
doaj   +1 more source