Results 191 to 200 of about 28,138,831 (356)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Evaluation of Flexor Digitorum Superficialis-Small Function: A Novel Dynamic Assessment Technique in Professional Music Performance. [PDF]

Hand (N Y)
Chen H, Lai HX, Venkateswaran S, Yang S, Stemple B, Zhang M, Liau ZQG.   +6 more
europepmc   +1 more source

Ground state geometries and hysteresis loops of small granular ferrofluids as function of coating

, 2006
A. Romero, J. Mejía‐López
openalex   +2 more sources

<p>MicroRNA-374b-5p Functions as a Tumor Suppressor in Non-Small Cell Lung Cancer by Targeting FOXP1 and Predicts Prognosis of Cancer Patients</p>

, 2020
Jianzhao Li, Xinfang Zhang, Jiaying Tang, Cuixue Gong   +3 more
openalex   +2 more sources

Erratum: Functions of microRNAs and related small RNAs in plants [PDF]

, 2006
Allison C. Mallory, Hervé Vaucheret
openalex   +1 more source

Matching small β functions using centroid jitter and two beam position monitors [PDF]

, 2020
C. A. Lindstrøm, Richard D’Arcy, M. J. Garland, P. González Caminal, B. Schmidt, S. Schröder, S. Wesch, Jens Osterhoff   +7 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Entire functions that share a small function with their derivatives

, 2004
Jianming Chang, Mingliang Fang
semanticscholar   +1 more source

The fundamental inequality for algebroid functions on annuli concerning small algebroid functions [PDF]

, 2019
Hong-Yan Xu, Zhaojun Wu
openalex   +1 more source