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Mitochondrial dynamics in autoimmune diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma   +5 more
wiley   +1 more source

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

open access: yesSmall Science, EarlyView.
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn   +4 more
wiley   +1 more source
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Small GTPase peripheral binding to membranes: molecular determinants and supramolecular organization.

Biochemical Society Transactions, 2019
Small GTPases regulate many aspects of cell logistics by alternating between an inactive, GDP-bound form and an active, GTP-bound form. This nucleotide switch is coupled to a cytosol/membrane cycle, such that GTP-bound small GTPases carry out their ...
François Peurois   +2 more
semanticscholar   +1 more source

Dynamin, a membrane-remodelling GTPase

Nature Reviews Molecular Cell Biology, 2012
Shawn M Ferguson
exaly  

Spatial and temporal coordination of mitosis by Ran GTPase

Nature Reviews Molecular Cell Biology, 2008
Paul R Clarke
exaly  

The small GTPase MoYpt7 is required for membrane fusion in autophagy and pathogenicity of Magnaporthe oryzae.

Environmental Microbiology, 2015
Xiao-hong Liu   +12 more
semanticscholar   +1 more source

G domain dimerization controls dynamin's assembly-stimulated GTPase activity

Nature, 2010
Joshua S Chappie   +2 more
exaly  

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