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Small intestinal bacterial overgrowth (SIBO) is a condition that is characterized by an increased number of bacteria in the small intestine or an existence of bacteria type that generally should not be in the small intestine.
Alvin Hartanto Kurniawan +3 more
doaj +1 more source
Small intestinal bacterial overgrowth syndrome
Human intestinal microbiota create a complex polymicrobial ecology. This is characterised by its high population density, wide diversity and complexity of interaction. Any dysbalance of this complex intestinal microbiome, both qualitative and quantitative, might have serious health consequence for a macro-organism, including small intestinal bacterial ...
Jan, Bures +7 more
openaire +2 more sources
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Colonoscopy does not induce small intestinal bacterial overgrowth
Background and Aim: Small intestinal bacterial overgrowth (SIBO) is associated with gastrointestinal pathology and colonoscopy. This endoscopic investigation could cause changes in gut flora including the occurrence of SIBO.
Ioana Gabriela Moraru +1 more
doaj +1 more source
Proton pump inhibitors (PPIs) are safe drugs that have been commonly used for many years by both general practitioners and specialists. They are widely used in the paediatric population, mainly in the treatment of gastroesophageal reflux disease, but ...
Zuzanna Wasielewska +2 more
doaj +1 more source
Interactions of intestinal epithelial cells with bacterial extracellular products [PDF]
The enteric microflora represents one of the densest microbial populations in the biological world; as a consequence, the intestinal immune system is constantly exposed to high concentrations of antigenic materials. One of the major frontline defences in
Patten, Daniel
core +3 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Small Intestinal Bacterial Overgrowth in Children: A State-Of-The-Art Review
Small intestinal bacterial overgrowth (SIBO) is a heterogenous and poorly understood entity characterised by an excessive growth of select microorganisms within the small intestine. This excessive bacterial biomass, in turn, disrupts host physiology in a
David Avelar Rodriguez +4 more
doaj +1 more source
Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome – An Update
Small intestinal bacterial overgrowth (SIBO) is one manifestation of gut microbiome dysbiosis and is highly prevalent in IBS (Irritable Bowel Syndrome). SIBO can be diagnosed either by a small bowel aspirate culture showing ≥103 colony-forming units (CFU)
Will Takakura +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

