Results 201 to 210 of about 689,619 (309)

Comparison of 2D, 3D <i>In Vitro</i>, and <i>Ex Vivo</i> Platforms for Modeling the Rat Small Intestine. [PDF]

Bioengineering (Basel)
Elias-Kirma S, McCoy R, Niekerk DV, Stoeger V, Oldroyd S, Sumner E, Savva A, Owens RM.   +7 more
europepmc   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Engineered vesicles enhance oral antibiotic absorption in proximal small intestine and mitigate gut dysbiosis. [PDF]

Nat Commun
Yu Y, Xu Y, Yu Z, Liu X, Guo J, Xiang M, Chen J, Widodo RT, Luo L.   +8 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Regeneration of the Gastrointestinal Tract After Using a Small Intestine Submucosa Patch-A Rat Model. [PDF]

Biomedicines
Toth T, Prisca RA, Szasz EA, Borka-Balas R, Borda A.   +4 more
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Quantifying Intestinal Glucose Absorption Using Isolated Vascularly Perfused Rat Small Intestine. [PDF]

Bio Protoc
Bæch-Laursen C, Bæch-Laursen S, Holst JJ.   +2 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Microbiome of the Proximal Small Intestine in Patients with Acute Pancreatitis. [PDF]

Diagnostics (Basel)
Kiselev VV, Koshechkin SI, Kurenkov AV, Odintsova VE, Zhigalova MS, Tyakht AV, Petrikov SS, Yartsev PA, Dmitriev IV.   +8 more
europepmc   +1 more source