Results 311 to 320 of about 442,180 (329)
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DNA and Cell Biology, 2017
Small nucleolar RNA host gene 12 (SNHG12) is a novel long noncoding RNA identified to be upregulated and functions as an oncogene in several cancers.
Xiaoyan Wang +6 more
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Small nucleolar RNA host gene 12 (SNHG12) is a novel long noncoding RNA identified to be upregulated and functions as an oncogene in several cancers.
Xiaoyan Wang +6 more
semanticscholar +2 more sources
Small Nucleolar RNA Expression Profiling in Cartilage
2020Osteoarthritis (OA) presents as a change in the articular chondrocyte phenotype. The origin of the phenotype change is poorly understood. Small nucleolar RNAs (snoRNAs) direct chemical modification of other RNA substrates and are involved in endoribonucleolytic pre-rRNA processing.
Tim J. M. Welting +2 more
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Small nucleolar RNAs and their genes in vertebrates
Russian Journal of Genetics, 2010Genes of box C/D small nucleolar RNAs (snoRNAs) were searched for in the genomes of members of all classes of vertebrates that do not belong to placental mammals. A tendency for an increase in the number of copies of snoRNA genes was observed in such vertebrates. This trend was most pronounced in anamnia (amphibians and fish).
Dmitri A. Kramerov, J. A. Makarova
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Small nucleolar RNAs and RNA-guided post-transcriptional modification
Essays in Biochemistry, 2013snoRNAs (small nucleolar RNAs) constitute one of the largest and best-studied classes of non-coding RNAs that confer enzymatic specificity. With associated proteins, these snoRNAs form ribonucleoprotein complexes that can direct 2′-O-methylation or pseudouridylation of target non-coding RNAs.
Lauren M. Lui, Todd M. Lowe
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Small Nucleolar RNAs Guide Ribosomal RNA Methylation
Science, 1996Two recent reports, one in Cell and one in the Journal of Molecular Biology , show that the newly described small nucleolar RNAs control the site of methylation of the ribosomal RNA (rRNA). Tollervey explains how these small RNAs accomplish this targeting and discusses the possible role of ...
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Small nucleolar RNA 47 promotes tumorigenesis by regulating EMT markers in hepatocellular carcinoma.
Minerva Medica, 2017BACKGROUND Hepatocellular carcinoma (HCC) is third leading cause of cancer-related death globally. Evidence suggest that small nucleolar RNAs (snoRNAs) have emerged as key regulators of tumor development and progression in HCC.
Guangcai Li +6 more
semanticscholar +1 more source
Probing RNA in Vivo with Methylation Guide Small Nucleolar RNAs
Methods, 2001Most box C/D small nucleolar RNAs (snoRNAs) direct the formation of 2'-O-methylated nucleotides in ribosomal RNA and, apparently, other RNAs present in the nucleolar complex. Sites to be modified are selected by a long (>10-nt) antisense guide sequence in the snoRNA and a distance measurement from a box D or D' element that follows the snoRNA guide ...
Ben Liu +2 more
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Indian Journal of Cancer, 2014
BACKGROUND Nonsmall cell lung cancer (NSCLC) is the major cause of cancer death worldwide. Increasing evidence shows that noncoding RNAs (ncRNAs) are widely involved in the development and progression of NSCLC.
J. You +6 more
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BACKGROUND Nonsmall cell lung cancer (NSCLC) is the major cause of cancer death worldwide. Increasing evidence shows that noncoding RNAs (ncRNAs) are widely involved in the development and progression of NSCLC.
J. You +6 more
semanticscholar +1 more source
Small nucleolar RNA and its potential role in breast cancer - A comprehensive review.
Biochimica et biophysica acta. Reviews on cancer, 2021Venzil Lavie Dsouza +5 more
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Deep Sequencing Analysis of Nucleolar Small RNAs: Bioinformatics
2016Small RNAs (size 20-30 nt) of various types have been actively investigated in recent years, and their subcellular compartmentalization and relative concentrations are likely to be of importance to their cellular and physiological functions. Comprehensive data on this subset of the transcriptome can only be obtained by application of high-throughput ...
Marikki Laiho, Baoyan Bai
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