Results 101 to 110 of about 549,904 (316)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

EFFICIENT TEAM BUILDING FOR ON-TIME PROJECTS [PDF]

When we think to software development projects we consider that a strong set of requirements is defined and team members always follow initial planning. Well, this was a specific orientation in traditional software developments methods and methodologies.
Dan Benţa, Ştefan Ioan Niţchi, Remus Felix Pop, Darius Șuta   +3 more
core  

Environmental Assessment for Small- and Medium-Scale Road Projects Implemented in Local Authority Areas: A Case Study from Thailand [PDF]

Journal of Construction in Developing Countries, 2009
In developing countries like Thailand, an Environmental Assessment (EA) is conducted only for projects prescribed by environmental legislation. Numerous projects, especially those that are small- and medium-scale in size and scope, are implemented in ...
Suparb Trethanya, Ranjith Perera
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

HYDRAULIC DESIGN OF SMALL BOAT HARBORS

, 1984
1. Purpose. This manual provides guidance for planning, layout, and design of small boat harbor projects. 1. Applicability. This manual applies to all HQUSACE/OCE elements and field operating activities having responsibility for the design of civil works
Small Boat Harbors
core  

Small Family Cohousing Projects. Santiago, Chile, 2024

ARQ
The Apartment Building in Virrey Avilés and the Small Family Cohousing are shaped by the constraints of their respective sites. The former occupies a typical lot in Buenos Aires, with a width of 8.66 meters, where circulations and collective spaces are ...
Gabriel Lagos Dittborn, Ignacia Larraín Castro, Javiera Paul   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Delivering successful IS/IT projects: Eight key elements from success criteria to review via appropriate management, methodologies and teams

, 1996
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In spite of decades of research, Information Systems/Information Technology (IS/IT) projects still often fail to deliver the objectives expected of them ...
Wateridge, John Frederick
core  

Analysis of the Characteristics of Production Activities in Chinese Design Organizations

Buildings
This study aims to systematically reveal, from the perspective of organizational scale, the differences between large and small architectural design organizations in China in terms of characteristics of production activities, technological capabilities ...
Xu Yang, Nikita Igorevich Fomin, Shuoting Xiao, Chong Liu, Jiaxin Li   +4 more
doaj   +1 more source