Results 71 to 80 of about 3,902,266 (287)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Hybrid mRMR and multi-objective particle swarm feature selection methods and application to metabolomics of traditional Chinese medicine [PDF]
PeerJ Computer ScienceMetabolomics data has high-dimensional features and a small sample size, which is typical of high-dimensional small sample (HDSS) data. Too high a dimensionality leads to the curse of dimensionality, and too small a sample size tends to trigger ...
Mengting Zhang +5 more
doaj +2 more sources
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Is IPO Underperformance a Peso Problem? [PDF]
Recent studies suggest that the underperformance of IPOs in the post-1970 sample may be a small sample effect or %u201CPeso%u201D problem. That is, IPO underperformance may result from observing too few star performers ex-post than were expected ex-ante.
Andrew Ang, Li Gu, Yael V. Hochberg
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Research on medical small sample data classification based on SMOTE and gcForest
物联网学报, 2023 Aiming at the problem of poor classification performance in traditional machine learning models caused by shallow model structure and complex data characteristics in small medical sample data, an combine multi- grained improved cascade forest (cgicForest)
Wenchang LIU +3 more
doaj +2 more sources
Improved small‐sample inference for functions of parameters in the k$$ k $$‐sample multinomial problem [PDF]
Scandinavian Journal of StatisticsAbstract When the target parameter for inference is a real‐valued, continuous function of probabilities in the ‐sample multinomial problem, variance estimation may be challenging. In small samples or when the function is nondifferentiable at the true parameter, methods like the nonparametric bootstrap or delta ...
Michael C. Sachs +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Uncovered Interest Rate Parity Over the Past Two Centuries [PDF]
Uncovered interest rate parity (UIP) is one of three key theoretical relations used in analytical work in both international finance and international monetary economics. The problem, however, is that UIP does not seem to hold up well empirically.
James R. Lothian, Liuren Wu
core