Results 241 to 250 of about 15,601,125 (299)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

A novel soil-water characteristic curve prediction model for unsaturated soil considering pore structure characteristics. [PDF]

PLoS One
Liu H, Yan D.
europepmc   +1 more source

Effect of cryotherapy on chemotherapy-induced peripheral neuropathy in patients with breast cancer treated with taxanes: a systematic review using the GRADE system. [PDF]

BMJ Neurol Open
Gravesen RE, Lendorf ME, Tankisi H, Bonde Jensen A.   +3 more
europepmc   +1 more source

The Effectiveness of the Revised PEACE Pack With Primary School Students: A Positive Approach to Bullying Reduction and Wellbeing. [PDF]

Health Promot J Austr
Shute RH, Slee PT.
europepmc   +1 more source

Distribution Patterns and Intraspecific Spatial Associations of Different Size Classes in <i>Krascheninnikovia ceratoides</i> (L.) Gueldenst. Populations Within the Tibetan Antelope Breeding Grounds of the West Kunlun Mountains. [PDF]

Plants (Basel)
Chen M, Huang K, Lai F, Jia X, Zhao D, Jia Y.   +5 more
europepmc   +1 more source

Evaluating large-scale propensity score adjustment when sample size is small. [PDF]

J Am Med Inform Assoc
Vereijken F, Reps JM, Suchard MA, Zhang L, Hripcsak G, Rijnbeek PR, Williams RD, Schuemie MJ.   +7 more
europepmc   +1 more source

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Two-stage designs with small sample sizes

Journal of Biopharmaceutical Statistics, 2022
When applying group-sequential designs in clinical trials with normally distributed outcomes, approximate critical values are often applied. Here, normally distributed test statistics are assumed which, however, are in fact t-distributed. For small sample sizes, the approximation may lead to a serious inflation of the type I error rate.
Meinhard Kieser, Geraldine Rauch, Maximilian Pilz   +2 more
openaire   +2 more sources