Results 121 to 130 of about 11,802,626 (213)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Small Farm Quarterly - Summer 2006 [PDF]

open access: yes, 2006
Small Farm Quarterly is for farmers and farm families — including spouses and children - who value the quality of life that smaller farms provide.CONTENTS: SMALL FARM PROGRAM UPDATE: Cornell Small Farms Program Update, Page 3; COMMUNITY/WORLD ...
Cornell Small Farms Program
core  

ASSESSING THE PERFORMANCE QUALITY OF MULTICRITERIA NEURAL NETWORK STATISTICAL ANALYSIS USING THE EXAMPLE OF TESTING THE HYPOTHESIS OF INDEPENDENCE OF SMALL SAMPLE DATA

open access: yesНадежность и качество сложных систем
Background. The purpose of the article is to create a quality criterion for assessing the effectiveness of neural network processing of small samples in multicriteria testing of the independence hypothesis. Materials and methods.
A.I. Ivanov, A.I. Ermakova
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Neural network analysis of small samples using a large number of statistical criteria to test the sequence of hypotheses about the value of mathematical expectations of correlation coefficients

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки
Background. The purpose of the article is to improve the accuracy of neural network estimates of correlation coefficients. Materials and methods. The correlation coefficient is one of the most significant second-order statistical points. When training
A.I. Ivanov   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Numerical algorithm for neural network recognition of persistent and antipersistent market conditions

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. In the last century, Hearst proposed his own statistical indicator, exploring the history of the Nile floods. Unfortunately, the Hurst index is insensitive to the sign of the correlation coefficients between the analyzed data and the time ...
Aleksandr I. Ivanov, Dmitriy V. Tarasov
doaj   +1 more source

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