Results 61 to 70 of about 559,527 (265)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Small signal stability enhancement of WSCC system using PSO based PSS

open access: yesFranklin Open
A number of synchronous generators are used in parallel in contemporary power systems. Studies are regularly carried out to make sure that the generators will work as intended in the case of any malfunctions or modifications to the system conditions. The
R. Ramya   +3 more
doaj   +1 more source

On Small Signal Frequency Stability under Virtual Inertia and the Role of PLLs

open access: yesEnergies, 2018
This paper presents a methodology that aims at identifying virtual inertia (VI) gain limitations from virtual synchronous generators (VSGs) while maintaining the frequency stability considering the delay associated with the frequency measurement process.
Sohail Khan   +3 more
doaj   +1 more source

Small Signal Stability Analysis of Grid Connected Photovoltaic

open access: yesIndonesian Journal of Electrical Engineering and Computer Science, 2017
This paper primarily focuses on the small signal stability analysis of a power system integrated with solar photovoltaics (PV). The test system used in this study is the IEEE 39-bus. The small signal stability of the test system are investigated in terms of eigenvalue analysis, damped frequency, damping ratio and participation factor.
Shalom Lim Zhu Aun   +2 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Two-Stage Small-Signal Stability-Assisted Framework Using Controllable Loads in Reconfigurable Microgrids

open access: yesIEEE Open Access Journal of Power and Energy
Reconfiguration in low-inertia microgrids (MGs) can often result in a critical small-signal stability margin. In this condition, the ability of inverter-based resources (IBRs) to provide voltage and frequency support may be insufficient.
Tossaporn Surinkaew   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Conventional P-ω/Q-V Droop Control in Highly Resistive Line of Low-Voltage Converter-Based AC Microgrid

open access: yesEnergies, 2016
In low-voltage converter-based alternating current (AC) microgrids with resistive distribution lines, the P-V droop with Q-f boost (VPD/FQB) is the most common method for load sharing.
Xiaochao Hou   +5 more
doaj   +1 more source

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