Results 161 to 170 of about 2,346,393 (314)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Wigner Functions of Time-Dependent Cat-like Even/Odd Superpositions of Nonlinear Coherent States. [PDF]

Entropy (Basel)
de Freitas MC, Dodonov VV.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Mechanical small bowel obstruction secondary to acute appendicitis. [PDF]

J Surg Case Rep
Barazi MD, Zanbrakji M, Safra A, Hegab A, Bade M, Bayasi M.   +5 more
europepmc   +1 more source

Combining market surveys and participatory approaches to map small ruminant mobility in three selected states in northern Nigeria [PDF]

Sandra I. Ijoma, Asma Mesdour, Muhammad-Bashir Bolajoko, Chika Nwosuh, Marion Bordier, Arnaud Bataille, Abdulrahman Adeiza, Wesley. D. Nafarnda, Elena Arsevska, Andrea Apolloni   +9 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Vaping during pregnancy and its impact on neonatal outcomes: A systematic review and meta-analysis. [PDF]

World J Clin Pediatr
Mylavarapu M, Chavali SM, Buddharaju AD, Veldurthy S, Cheruvu P, Parikh AG.   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Caudal esophageal achalasia in a Quarter Horse colt. [PDF]

J Vet Intern Med
Alvarado Soto GJ, Maldonado M, Armentrout A, Woolard K, Aleman M, Giaretta P, Willis AT.   +6 more
europepmc   +1 more source

Characterizing pathways of seafood access in small island developing states [PDF]

Katherine Seto, Whitney R. Friedman, Jacob G. Eurich, Jessica A. Gephart, Jessica Zamborain‐Mason, M. Keith Sharp, Erietera Aram, Aritita Tekaieti, Aranteiti Tekiau, Christopher D. Golden   +9 more
openalex   +1 more source