Results 41 to 50 of about 8,511,971 (350)

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity

eLife
Gonorrhea, which is caused by Neisseria gonorrhoeae, is the second most reported sexually transmitted infection worldwide. The increasing appearance of isolates that are resistant to approved therapeutics raises the concern that gonorrhea may become ...
Jingbo Kan, Adrian Morales-Amador, Yozen Hernandez, Melinda A Ternei, Christophe Lemetre, Logan W Maclntyre, Nicolas Biais, Sean F Brady   +7 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa

Frontiers in Neuroscience, 2017
Despite mutations in the rod phosphodiesterase 6-alpha (PDE6A) gene being well-recognized as a cause of human retinitis pigmentosa, no definitive treatments have been developed to treat this blinding disease.
Freya M. Mowat, Freya M. Mowat, Laurence M. Occelli, Joshua T. Bartoe, Kristen J. Gervais, Ashlee R. Bruewer, Janice Querubin, Astra Dinculescu, Sanford L. Boye, William W. Hauswirth, Simon M. Petersen-Jones   +10 more
doaj   +1 more source

Effect of Time Reversal Symmetry Breaking on the Density of States in Small Superconducting Grains

, 1999
We show that in ultra-small superconducting grains any concentration of magnetic impurities or infinitely small orbital effect of magnetic field leads to destruction of the hard gap in the tunneling density of states.
A. A. Abrikosov, A. I. Larkin, B. I. Halperin, B. L. Altshuler, B. N. Narozhny, C. T. Black, D. C. Ralph, D. C. Ralph, H.-Y. Kee, I. Giaver, I. L. Aleiner, I. M. Lifshitz, I. S. Beloborodov, J. Bardeen, J. Zittartz, L. P. Gor'kov, M. L. Mehta, M. Tinkham, N. N. Bogolyubov, P. W. Anderson, Y. Nambu   +20 more
core   +1 more source

Strong Correlation to Weak Correlation Phase Transition in Bilayer Quantum Hall Systems [PDF]

, 2001
At small layer separations, the ground state of a nu=1 bilayer quantum Hall system exhibits spontaneous interlayer phase coherence and has a charged-excitation gap E_g.
A. H. MacDonald, A. H. MacDonald, A. Sawada, B. I. Halperin, I. B. Spielman, J. P. Eisenstein, John Schliemann, K. Moon, K. Moon, K. Yang, N. E. Bonesteel, R. Côte, S. He, S. M. Girvin, S. Q. Murphy, Y. N. Joglekar   +15 more
core   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Anderson localization of polaron states

, 2002
Using the vanishing of the typical polaron tunneling rate as an indicator of the breakdown of itinerancy, we study the localization of polaron states in a generic model for a disordered polaronic material.
A. Georges, A.J. Millis, A.S. Alexandrov, D.J. Thouless, E. Miranda, F.X. Bronold, Franz X. Bronold, G. Wellein, G. Wellein, H. DeRaedt, H. Fehske, H. Löwen, H. Sumi, Holger Fehske, J. Boncă, J. Ranninger, J.H. Schön, L.D. Landau, M. Capone, M.H. Cohen, P.A. Lee, P.E. Parris, P.W. Anderson, P.W. Anderson, R. Abou-Chacra, R.J. Elliot, S. Ciuchi, V. Dobrosavljević, V. Dobrosavljević, W. Stephan   +29 more
core   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source