Results 181 to 190 of about 5,996,346 (272)
ABSTRACT Helicobacter pylori infection is characterized by chronic gastric inflammation driven by persistent activation of innate immune signalling pathways. Outer membrane vesicles (OMVs) released by H. pylori are important mediators of host–pathogen interactions. Although several mechanisms of OMV internalization have been described, how specific OMV‐
Mariaignacia Rubilar +6 more
wiley +1 more source
A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain +13 more
wiley +1 more source
Metabolization of Flavan‐3‐ol Oligomers by Eggerthella lenta, a Human Gut Bacterium
Novel human gut bacterial strains were isolated and characterized for their ability to metabolize flavan‐3‐ols. While Eggerthella lenta and Flavonifractor plautii metabolized flavan‐3‐ol monomers, only E. lenta converted B‐ and A‐type procyanidins, demonstrating that this gut bacterium can metabolize flavan‐3‐ol oligomers.
Ruben Halifa +10 more
wiley +1 more source
Abstract Reliable detection of structural variants (SVs) and copy number variations (CNVs) is crucial in the contemporary diagnostics of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). However, limitations of commonly used conventional and molecular cytogenetic methods may hinder the accurate genetic characterization of patients.
Anna Bekő +21 more
wiley +1 more source
Deep Learning Predicts Hematopoietic Stem Cell Aging From 3D Chromatin Images
Deep learning identifies age‐associated chromatin architecture signatures in 3D images of hematopoietic stem cell nuclei, providing an interpretable imaging biomarker that distinguishes young from aged cells and detects chromatin rejuvenation after treatment.
Pablo Iáñez Picazo +5 more
wiley +1 more source
Cat Eye Syndrome in a Sudanese Infant: Congenital Cataract in the Absence of Iris Coloboma: A Case Report. [PDF]
Khalid R, Fadl-Elmula I.
europepmc +1 more source
B chromosomes put the 'super' in supernumerary. [PDF]
Samuelson KB, Hanlon SL.
europepmc +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source

