Results 31 to 40 of about 5,934,940 (292)

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Exploring atitudes towards immigrants in Cape Town, South Africa [PDF]

, 2011
Earlier studies conducted in South Africa suggest that negative attitudes towards immigrants are widespread and driven by resource strain, issues around national identity, and the process of ‘othering’.
Murambiwa, Rutendo
core   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Geobranding of an abandoned small town: analysing problems and opportunities from the perspective of systems theory

Вестник университета
The article investigates the problem of small towns in the Russian Federation that are already abandoned or being abandoned in the context of solving tasks of sustainable development of territories.
I. Yu. Aleksandrova
doaj   +1 more source

Synthetic Shewanella‐Bacillus Microbial Consortia for Enhanced Metal Oxide Leaching From Spent Lithium‐Ion Batteries Using Brewing Wastewater as Leaching Agent

Advanced Science, EarlyView.
A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang, Chunxiao Qiao, Huichun Liu, Yiyun Wang, Yan Liu, Huan Yu, Junqi Zhang, Chao Li, Deguang Wu, Qulai Tang, Zhiwen Wang, Danni Zhang, Dake Xu, Feng Li, Hao Song   +14 more
wiley   +1 more source

'The names we give' : narratives of identity and positioning of the 'helpers' in Pofadder [PDF]

, 2012
Includes bibliographical references.This thesis examines the subjective constructions of identity in the narratives of 'helpers' in the small town of Pofadder in the Northern Cape. It focuses on the impact of historical narratives on their intersectional
Arogundade, Emma
core   +1 more source

Corrosion-fatigue synergy in steel bridges: Mechanisms and mechanical degradation

Results in Engineering
This study pioneers the investigation of asynchronous corrosion-fatigue coupling effects on structural steel degradation, addressing a critical gap in understanding synergistic damage mechanisms under combined environmental and mechanical stresses ...
Lizhen Huang, Li Wan, Zifan Zuo, Zhiqin Cai, Xianwei Wang, Hui Liu, Jingwen Liu   +6 more
doaj   +1 more source

Combining Sanitary Inspection and Water Quality Data in Western Uganda: Lessons Learned from a Field Trial of Original and Revised Sanitary Inspection Forms

Resources, 2020
Risk assessment for drinking water systems combines sanitary inspections (SI) and water quality testing and is critical for effectively managing the safety of these systems.
D. Daniel, Josphine Gaicugi, Richard King, Sara J. Marks, Giuliana Ferrero   +4 more
doaj   +1 more source

Les bourgs ruraux face au vieillissement de la population : des stratégies d’attractivité résidentielle en décalage avec les dynamiques démographiques et migratoires ?

Espace populations sociétés, 2023
For several decades, the numerous very small towns structuring the French countryside have been facing a significant ageing of their population alongside series of structural processes, which strained their historical role in rural areas.
Anton Paumelle
doaj   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source