Results 261 to 270 of about 203,748 (298)

Small open reading frames in 5′ untranslated regions of mRNAs

open access: closedComptes Rendus. Biologies, 2003
Using the 5′-end sequence data from ‘oligo-capped’ cDNAs, we generated a representative full-length cDNA dataset for 4870 RefSeq entries, and analyzed the 5′ untranslated region (UTR) of these genes. To our surprise, about half of the 4870 genes had an upstream ATG before the ATG that starts the longest open reading frame (ORF), suggesting that about ...
Riu Yamashita   +3 more
openalex   +3 more sources

Characterization of the Small Untranslated RNA RyhB and Its Regulon inVibrio cholerae [PDF]

open access: closedJournal of Bacteriology, 2005
ABSTRACTNumerous small untranslated RNAs (sRNAs) have been identified inEscherichia coliin recent years, and their roles are gradually being defined. However, few of these sRNAs appear to be conserved inVibrio cholerae, and both identification and characterization of sRNAs inV. choleraeremain at a preliminary stage. We have characterized one of the few
Brigid M. Davis   +4 more
openalex   +3 more sources

Polymorphisms of the PD‐L1 gene 3′‐untranslated region are associated with the expression of PD‐L1 in non‐small cell lung cancer

open access: closedGenes, Chromosomes and Cancer, 2023
AbstractRecent results show that polymorphisms of programmed death ligand 1 (PD‐L1, also known as CD274 or B7‐H1) might be used as a possible marker for effectiveness of chemotherapy and cancer risk. However, the effect of PD‐L1 gene variations on PD‐L1 expression remain unclear.
Yoshihito Ohhara   +8 more
openalex   +3 more sources

A 3′-Untranslated Region Polymorphism in IGF1 Predicts Survival of Non–Small Cell Lung Cancer in a Chinese Population [PDF]

open access: closedClinical Cancer Research, 2010
Abstract Purpose: Disruption of the balance of insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP3) has been implicated in the etiology and progression of lung and other cancers. Single nucleotide polymorphisms (SNP) in IGF1 and IGFBP3 have been reported to be associated with the expression of the IGF-I/IGFBP3 axis ...
Mingfeng Zhang   +11 more
openalex   +3 more sources

AEG-1 3′-untranslated region functions as a ceRNA in inducing epithelial–mesenchymal transition of human non-small cell lung cancer by regulating miR-30a activity

open access: closedEuropean Journal of Cell Biology, 2014
Competitive endogenous messenger RNA regulates the transcription of other RNA moleculars through competing for the shared microRNAs. This study was carried out to explore the regulation of AEG-1 messenger RNA as a competitive endogenous RNA in the epithelial-mesenchymal transition and metastasis of lung tumor cells.
Kunmei Liu   +7 more
openalex   +3 more sources

Association of miR-502-binding site single nucleotide polymorphism in the 3′-untranslated region of SET8 and TP53 codon 72 polymorphism with non-small cell lung cancer in Chinese population [PDF]

open access: closedActa Biochimica et Biophysica Sinica, 2013
The objective of this study was to identify whether the miR-502-binding site single nucleotide polymorphism (SNP) in the 3'-untranslated region (3'-UTR) of set domain-containing protein 8 (SET8) and the tumor protein p53 (TP53) codon 72 polymorphism were associated with the risk for non-small cell lung cancer (NSCLC), either independently or jointly ...
Shaodi Yang   +6 more
openalex   +3 more sources

Home - About - Disclaimer - Privacy