Results 271 to 280 of about 203,748 (298)

Transgenic overexpression of UIP1, an interactor of the 3′ untranslated region of the Rubisco small subunit mRNA, increases rice tolerance to drought

Plant Biotechnology Reports, 2012
Gene regulation at the post-transcriptional level is a well-organized process to adjust plants in response to environmental changes. Here, we identified a novel RNA-binding protein (RBP) possessing a CBS (cystathionine-β-synthase) domain through yeast three-hybrid screening.
Su Hyun Park, Jin Seo Jeong, Mark Christian Felipe R. Redillas, Harin Jung, Seung Woon Bang, Youn Shic Kim, Ju‐Kon Kim   +6 more
openalex   +2 more sources

Translation of the Placenta Growth Factor mRNA is Severely Affected by a Small Open Reading Frame Localized in the 5′ Untranslated Region

Growth Factors, 1993
The recently identified placenta growth factor gene (PIGF) code for a protein related to the vascular permeability factor (VPF). We present evidence indicating that expressing of this gene could be regulated at the post-transcriptional level. The region upstream to the coding region of PIGF mRNA contains a small open reading frame (ORF), potentially ...
Domenico Maglione, Valente Guerriero, Marco Rambaldi, Giuseppe Russo, M. Graziella Persico   +4 more
openalex   +3 more sources

Long-term BRCA1 down-regulation by small hairpin RNAs targeting the 3' untranslated region.

Neoplasma, 2008
Mutations in the BRCA1 gene are responsible for the majority of hereditary breast/ovarian cancers. The functional significance of many mutations/splicing variants identified during the screening of high-risk individuals is difficult to predict due to the lack of in vitro functional tests correlating sequence variants with a risk of cancer development ...
Eva Vondrušková, Radek Malı́k, Jan Ševčı́k, Petra Kleiblová, Zdeněk Kleibl   +4 more
openalex   +2 more sources

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G-Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Journal of Medicinal Chemistry, 2015
Up-regulation of a disintegrin and metalloproteinase 10 (ADAM10) to prevent the formation of β-amyloid (Aβ) peptides might be a promising strategy to treat Alzheimer's disease (AD). RNA G-quadruplex motif within the 5'-UTR of the ADAM10 mRNA is an inhibitory element for ADAM10 translation.
Jie Dai, Zhen-Quan Liu, Xiaoqin Wang, Jing Lin, Pei-Fen Yao, Shi‐Liang Huang, Tian‐Miao Ou, Jia‐Heng Tan, Ding Li, Lian‐Quan Gu, Zhi‐Shu Huang   +10 more
openalex   +3 more sources

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Co-expression analysis of small RNAs and untranslated regions in Rhodospirillum rubrum

Bacterial small RNAs (sRNAs) are regulatory elements often mentioned in the context of stress response. So are polyhydroxyalkanoates (PHAs), a possible replacement for conventional plastics, are frequently produced by bacteria facing stress conditions.
Heřmánková, Kristýna, Sedlář, Karel   +1 more
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa, Joyce M Slingerland   +1 more
exaly  

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg, William L Hwang, Anirban Maitra   +2 more
exaly  

Oral complications of cancer and cancer therapy

Ca-A Cancer Journal for Clinicians, 2012
Joel B Epstein, Rene-Jean Bensadoun, Andrei Barasch   +2 more
exaly  

The financial burden and distress of patients with cancer: Understanding and stepping‐up action on the financial toxicity of cancer treatment

Ca-A Cancer Journal for Clinicians, 2018
Pricivel M Carrera, Hagop M Kantarjian, Victoria S Blinder   +2 more
exaly