Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans
G3: Genes, Genomes, Genetics, 2016 The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs.
Zhiji Ren +3 more
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Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells [PDF]
, 2017 Background: Previously, we determined that heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) functions as an intracellular physiologic sensor of folate deficiency.
Antony, Aśok C. +7 more
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The role of small non-coding RNAs (sncRNAs) in male infertility: A scoping review
Asian Pacific Journal of Reproduction, 2023 Objective: To give a brief overview of the field of epigenetics and the potential predictive power that small non-coding RNA (sncRNA) may hold in relation to improving the treatment and diagnosis of male infertility.
Hacer Kaya Cakir, Onur Eroglu
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Ornithine Decarboxylase mRNA is Stabilized in an mTORC1-dependent Manner in Ras-transformed Cells [PDF]
, 2012 Upon Ras activation, ODC (ornithine decarboxylase) is markedly induced, and numerous studies suggest that ODC expression is controlled by Ras effector pathways. ODC is therefore a potential target in the treatment and prevention of Ras-driven tumours. In
Albig +51 more
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The Journal of Poultry Science, 2009 Glutathione peroxidase 1 (cellular glutathione peroxidase, EC 1.11.1.9 (GPX1)) is an antioxidant enzyme that plays an important role in scavenging reactive oxygen species to protect cells from oxidative damage.
Sopon Wilaison, Makoto Mori
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A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]
, 2019 Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D. +2 more
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Test MicroRNA Target with in vitro Cell Culture Luciferase Assay
Bio-Protocol, 2013 MicroRNAs (miRNAs) are small non-coding RNAs of 21-24 nucleotides in length that modulate gene expression by targeting the untranslated region (UTR) of mRNA.
Nathalie Coré
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Frontiers in Cellular and Infection Microbiology, 2022 The genus Flavivirus of the Flaviviridae family includes important viruses, such as Dengue, Zika, West Nile, Japanese encephalitis, Murray Valley encephalitis, tick-borne encephalitis, Yellow fever, Saint Louis encephalitis, and Usutu viruses.
Rodolfo Gamaliel Avila-Bonilla +1 more
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Sequence analysis and genomic organization of Aphid lethal paralysis virus: a new member of the family Dicistroviridae [PDF]
, 2002 The complete nucleotide sequence of the genomic RNA of an aphid-infecting virus, Aphid lethal paralysis virus (ALPV), has been determined. The genome is 9812 nt in length and contains two long open reading frames (ORFs), which are separated by an ...
Clerivet, A. +5 more
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Regulatory effect of 5'tRF-LysCTT on ferroptosis in mouse cardiomyocytes and its mechanism [PDF]
精准医学杂志Objective To investigate the regulatory effect of tRNA-derived small RNA (tsRNA) on ferroptosis in mouse cardiomyocytes and its mechanism. Methods RT-qPCR was used to measure the relative expression level of 5'tRF-LysCTT in the heart, liver, spleen ...
ZHAO Yan, WANG Kai, CHENG Xueli, WANG Kun
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