Results 71 to 80 of about 203,748 (298)
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Microproteins in skeletal muscle: hidden keys in muscle physiology
Recent advances in the transcriptomics, translatomics, and proteomics have led us to the exciting new world of functional endogenous microproteins. These microproteins have a small size and are derived from small open reading frames (smORFs) of RNAs ...
Bernardo Bonilauri, Bruno Dallagiovanna
doaj +1 more source
Straight from the horse’s mouth: children’s reception of dubbed animated films in Spain [PDF]
Reception studies in the field of audiovisual translation (AVT) have increased considerably in the last two decades, including the target viewer in the picture.
de los Reyes Lozano, Julio
core
Identification of novel post-transcriptional features in olfactory receptor family mRNAs. [PDF]
Olfactory receptor (Olfr) genes comprise the largest gene family in mice. Despite their importance in olfaction, how most Olfr mRNAs are regulated remains unexplored.
Espinoza, Josh L +3 more
core +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Recent advances in understanding the role of miRNAs in exosomes and their therapeutic potential
MicroRNAs (miRNAs) are small endogenous non-protein coding RNAs that range in size from 19–25 nucleotides. Thousands of miRNA genes have been identified in a variety of organisms, suggesting genetic exchange and distribution among species.
Xiang-yang MIAO
doaj +1 more source
Cloning, Expression, Sequence Analysis and Homology Modeling of the Prolyl Endoprotease from Eurygaster integriceps Puton [PDF]
Eurygaster integriceps Puton, commonly known as sunn pest, is a major pest of wheat in Northern Africa, the Middle East and Eastern Europe. This insect injects a prolyl endoprotease into the wheat, destroying the gluten.
Clack, Beatrice A. +5 more
core +3 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Huan Song,1,* Dian Xu,1,* Peiyi Shi,1 Biyu He,1 Zhongqi Li,1 Ye Ji,1 Charles Kwaku Agbeko,1 Jianming Wang1,2 1Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, People’s ...
Song H +7 more
doaj
Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]
To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD +6 more
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