Results 111 to 120 of about 1,601,455 (409)

Large Vessel Disease Modifies the Relationship Between Kidney Injury and Cerebral Small Vessel Disease

Frontiers in Neurology, 2018
Background: Recent studies have shown that renal disease is associated with magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD), independent of traditional vascular risk factors.
Dong-Hui Ao, Fei-Fei Zhai, Fei Han, Li-Xin Zhou, Jun Ni, Ming Yao, Ding-Ding Zhang, Ming-Li Li, Xiao-Hong Fan, Zheng-Yu Jin, Li-Ying Cui, Shu-Yang Zhang, Yi-Cheng Zhu   +12 more
doaj   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Prevention and Management of Cerebral Small Vessel Disease [PDF]

Journal of Stroke, 2015
Lacunar infarcts/lacunes, white matter hyperintensities (WMH), and cerebral microbleeds (CMBs) are considered various manifestations of cerebral small vessel disease (SVD).
Vincent Mok, Jong S. Kim
doaj   +1 more source

Quantification of Morphological Features in Non-Contrast Ultrasound Microvasculature Imaging [PDF]

arXiv, 2018
Morphological features of small vessels provide invaluable information regarding underlying tissue, especially in cancerous tumors. This paper introduces methods for obtaining quantitative morphological features from microvasculature images obtained by non-contrast ultrasound imaging.
arxiv  

Automatic ultrasound vessel segmentation with deep spatiotemporal context learning [PDF]

arXiv, 2021
Accurate, real-time segmentation of vessel structures in ultrasound image sequences can aid in the measurement of lumen diameters and assessment of vascular diseases. This, however, remains a challenging task, particularly for extremely small vessels that are difficult to visualize.
arxiv  

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease [PDF]

, 2015
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs.
Alver, M, Anand, SS, Ardissino, D, Armasu, SM, Assimes, TL, Auro, K, Bertram, L, Beutner, F, Bjonnes, A, Boerwinkle, E, Borecki, IB, Bottinger, EP, Buring, JE, Chambers, JC, Chasman, DI, Chen, S, Clarke, R, Collins, R, Consortium, C, Cupples, LA, Danesh, J, de Andrade, M, de Vries, PS, Dedoussis, G, Dehghan, A, Deloukas, P, Demuth, I, Elosua, R, Epstein, SE, Erdmann, J, Esko, T, Farrall, M, Feitosa, MF, Ford, I, Franceschini, N, Franco, OH, Franzosi, MG, Frossard, P, Gauguier, D, Gieger, C, Goel, A, Goodall, AH, Gottesman, O, Grace, C, Granger, CB, Gu, D, Gudnason, V, Gustafsson, S, Haber, M, Hall, AS, Hall, LM, Hamsten, A, Han, B-G, Harris, TB, Hazen, SL, Hengstenberg, C, Hofman, A, Hopewell, JC, Huang, J, Huang, J, Hwang, S-J, Ingelsson, E, Iribarren, C, Jalilzadeh, S, Jukema, JW, Kanoni, S, Karhunen, PJ, Kathiresan, S, Kessler, T, Kim, B-J, Kim, YK, Kleber, ME, Koenig, IR, Kooner, JS, Kullo, IJ, Kyriakou, T, Lannfelt, L, Lau, KW, Lehtimaki, T, Lieb, W, Lind, L, Lindgren, CM, Lokki, M-L, Loos, RJF, Lu, X, Lu, Y, Lyytikainen, L-P, Maerz, W, Magnusson, PK, Mallick, NH, McPherson, R, Mehra, N, Meitinger, T, Melander, O, Memon, F-U-R, Metspalu, A, Mihailov, E, Morris, AP, Morrison, AC, Nelson, CP, Nieminen, MS, Nikpay, M, O'Donnell, CJ, Palmer, CN, Pedersen, NL, Perola, M, Pervjakova, N, Peters, A, Qu, L, Quertermous, T, Rader, DJ, Rallidis, LS, Rasheed, A, Reilly, MP, Ridker, PM, Ripatti, S, Roberts, R, Rose, LM, Saleheen, D, Salfati, E, Salomaa, V, Samani, NJ, Samuel, M, Sanghera, DK, Saxena, R, Scholz, M, Schunkert, H, Schwartz, SM, Seedorf, U, Shah, SH, Sinisalo, J, Smith, AV, Stewart, AF, Stirrups, KE, Stott, DJ, Thiery, J, Thompson, JR, Tikkanen, E, Trompet, S, Uitterlinden, A, van Zuydam, NR, Wang, L, Watkins, H, Webb, TR, Willenborg, C, Won, H-H, Yang, X, Zalloua, PA, Zaman, KS, Zeng, L, Zhang, W, Zhao, W   +151 more
core   +4 more sources

Age-related cerebral small vessel disease and inflammaging

Cell Death and Disease, 2020
The continued increase in global life expectancy predicts a rising prevalence of age-related cerebral small vessel diseases (CSVD), which requires a better understanding of the underlying molecular mechanisms.
Tiemei Li, Yinong Huang, W. Cai, Xiaodong Chen, X. Men, T. Lu, A. Wu, Zhengqi Lu   +7 more
semanticscholar   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Age-dependent expression of VEGFR2 in deep brain arteries in small vessel disease, CADASIL, and healthy brains [PDF]

, 2016
Vascular myocytes are central to brain aging. Small vessel disease (SVD; arteriolosclerosis) is a widespread cause of lacunar stroke and vascular dementia, and is characterised by fibrosis and depletion of vascular myocytes in small penetrating ...
Anum S. Arwani, Argaw, Argaw, Atticus H. Hainsworth, Barker, Boer, Bridges, Brockington, Chanakira, Cheng, Dassan, Duval, Esiri, Fernando, Fisher, Fiyyaz Ahmed-Jushuf, Giwa, Greenberg, Guo, Hachinski, Hainsworth, Hayakawa, Hogervorst, Hohman, Ishida, Kalaria, Krum, Lammie, Lammie, Leslie R. Bridges, Margaret M. Esiri, Medana, Miao, Murdaca, Nadim S. Jiwa, Peter Foot, Potente, Prins, Rahimi, Raj N. Kalaria, Reeson, Religa, Rossi, Shintani, Storkebaum, Stowe, Stowe, Whitman, Wittko-Schneider, Yamamoto, Yao   +50 more
core   +1 more source