Results 141 to 150 of about 1,601,455 (409)

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Association between arterial stiffness, cerebral small vessel disease and cognitive impairment: A systematic review and meta-analysis [PDF]

, 2015
Arterial stiffness may be a cause of cerebral small vessel disease and cognitive impairment. We therefore performed a systematic review and meta-analysis of studies on the association between stiffness, cerebral small vessel disease and cognitive ...
Henry, Ronald M. A., Launer, Lenore J., Protogerou, Athanase D., Schram, Miranda T., Stehouwer, Coen D. A., van Sloten, Thomas T.   +5 more
core   +1 more source

Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of acute cerebral microinfarcts (ACMIs) in patients with CADASIL.
Xuejiao Men, Hui Li, Zhuoxin Guo, Bin Qin, Hengfang Ruan, Ruipeng Cai, Bingjun Zhang, Aimin Wu, Lei Wei, Yongqiang Dai, Haiyan Li, Zhengqi Lu   +11 more
wiley   +1 more source

Retinal Vessel Segmentation Based on Conditional Deep Convolutional Generative Adversarial Networks [PDF]

arXiv, 2018
The segmentation of retinal vessels is of significance for doctors to diagnose the fundus diseases. However, existing methods have various problems in the segmentation of the retinal vessels, such as insufficient segmentation of retinal vessels, weak anti-noise interference ability, and sensitivity to lesions, etc. Aiming to the shortcomings of existed
arxiv  

Neuroimaging standards for research into small vessel disease—advances since 2013

Lancet Neurology, 2023
M. Duering, G. Biessels, A. Brodtmann, Christopher P L H Chen, C. Cordonnier, F.‐E. Leeuw, S. Debette, R. Frayne, E. Jouvent, N. Rost, A. Telgte, R. Salman, W. Backes, H. Bae, Rosalind Brown, H. Chabriat, A. Luca, C. DeCarli, Anna Dewenter, F. Doubal, M. Ewers, T. Field, A. Ganesh, S. Greenberg, K. Helmer, S. Hilal, A. Jochems, H. Jokinen, Hugo J. Kuijf, B. Lam, J. Lebenberg, B. MacIntosh, P. Maillard, Vincent C. T. Mok, L. Pantoni, S. Rudilosso, C. Satizabal, M. Schirmer, R. Schmidt, Colin Smith, J. Staals, M. Thrippleton, S. V. Veluw, P. Vemuri, Yilong Wang, D. Werring, M. Zedde, R. Akinyemi, O. Brutto, H. Markus, Yicheng Zhu, E. Smith, M. Dichgans, J. Wardlaw   +53 more
semanticscholar   +1 more source

Serotonergic and Dopaminergic Function in Neuropsychiatrically Asymptomatic People With HIV on Antiretroviral Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau, Anna Lyndaker, Swati Shah, Paul Wakim, Amelia Mitchell, Cynthia Monroe, Alan Kim, Tracy L. Cropper, Govind Nair, Joseph Snow, Bryan R. Smith, Avindra Nath, Dima A. Hammoud   +12 more
wiley   +1 more source

HTRA1-Related Cerebral Small Vessel Disease: A Review of the Literature

Frontiers in Neurology, 2020
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is clinically characterized by early-onset dementia, stroke, spondylosis deformans, and alopecia.
M. Uemura, H. Nozaki, Taisuke Kato, A. Koyama, N. Sakai, Shoichiro Ando, M. Kanazawa, N. Hishikawa, Y. Nishimoto, K. Polavarapu, A. Nalini, A. Hanazono, D. Kuzume, A. Shindo, M. El‐Ghanem, A. Abe, A. Sato, Mari Yoshida, T. Ikeuchi, I. Mizuta, T. Mizuno, O. Onodera   +21 more
semanticscholar   +1 more source

Brain Characteristics in Patients With Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disorder by 7.0 Tesla MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su, Joseph Kuchling, Chenyang Gao, Thoralf Niendorf, Carsten Finke, Zhe Zhang, Ai Guo, Jing Jing, De‐Cai Tian, Yu‐Jing Li, Mengting Zhang, Xiaoyu Shi, Xinyao Liu, Huabing Wang, Yaou Liu, Claudia Chien, Michael Levy, Yunyun Duan, Friedemann Paul, Fu‐Dong Shi   +19 more
wiley   +1 more source

Pulse Pressure, White Matter Hyperintensities, and Cognition: Mediating Effects Across the Adult Lifespan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate whether pulse pressure or mean arterial pressure mediates the relationship between age and white matter hyperintensity load and to examine the mediating effect of white matter hyperintensities on cognition. Methods Demographic information, blood pressure, current medication lists, and Montreal Cognitive Assessment ...
Jade Hannan, Sarah Newman‐Norlund, Natalie Busby, Sarah C. Wilson, Roger Newman‐Norlund, Chris Rorden, Julius Fridriksson, Leonardo Bonilha, Nicholas Riccardi   +8 more
wiley   +1 more source

VC-Net: Deep Volume-Composition Networks for Segmentation and Visualization of Highly Sparse and Noisy Image Data [PDF]

arXiv, 2020
The motivation of our work is to present a new visualization-guided computing paradigm to combine direct 3D volume processing and volume rendered clues for effective 3D exploration such as extracting and visualizing microstructures in-vivo. However, it is still challenging to extract and visualize high fidelity 3D vessel structure due to its high ...
arxiv