Results 321 to 330 of about 1,601,455 (409)

Deep learning assisted retinal microvasculature assessment and cerebral small vessel disease in Fabry disease. [PDF]

Orphanet J Rare Dis
Li Y, Zhou X, Li J, Zhao Y, Yuan Y, Yang B, Xu J, Wei Q, Yan X, Zhang W, Wu Y.   +10 more
europepmc   +1 more source

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

Advanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui, Furong Huang, Kun Fang, Jingyue Yan, Yuebao Zhang, Diana D. Kang, Yufan Zhou, Yue Zhao, Jeffrey I. Everitt, William Hankey, Andrew J Armstrong, Jiaoti Huang, Hongyan Wang, Victor X. Jin, Yizhou Dong, Qianben Wang   +15 more
wiley   +1 more source

Deep learning-based automated segmentation for the quantitative diagnosis of cerebral small vessel disease via multisequence MRI. [PDF]

Front Neurol
Zhao H, Zhang M, Tang W, Jin L, Tang J, Shi L, Deng X, Fu J, Zou W.   +8 more
europepmc   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

The Relationship Between Blood Omega-3 Levels and the Small Vessel Disease in Ischemic Stroke Patients: A Case-Control Study. [PDF]

Health Sci Rep
Hezarkhani LA, Mansouri K, Salari N, Ammari-Allahyari M, Shahbazi H, MohamadYari M, Mohammadi M.   +6 more
europepmc   +1 more source

Supplementary Material for: Correlation of Cognition and SPECT Perfusion: Easy Z Score and SPM Analysis of a Pilot Sample with Cerebral Small Vessel Disease

, 2013
John G. Baker, Amy J. Williams, David S. Wack, Robert S. Miletich   +3 more
openalex   +2 more sources

Bioengineered Tumor‐Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance

Advanced Science, EarlyView.
The upregulated CCL24 in CRC liver metastasis promotes the formation of inflammatory tumor‐associated fibroblast subsets and induces resistance to bevacizumab therapy. Downregulation of CCL24 significantly increased sensitivity to antiangiogenic therapy in CRC mouse model. Hence, a novel therapeutic target is identified for patients with CRC with liver
Junjiang Wang, Chunsheng Liu, Ping Wang, Zhiyuan Liu, Weixian Hu, Zejian Lv, Chengzhi Huang, Xueqing Yao   +7 more
wiley   +1 more source

Strengthening the link between periodic leg movements during sleep and cerebral small vessel disease. [PDF]

Sleep
Ferri R, Lanza G, Mogavero MP.
europepmc   +1 more source

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management

Advanced Science, EarlyView.
Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang, Longfei Li, Yiran Hu, Zhou Li, Wei Hua   +4 more
wiley   +1 more source