Results 41 to 50 of about 2,661,773 (283)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

BMEMat
Chronic wounds are wounds that are difficult to heal or do not follow the normal healing process. These include pressure ulcers, diabetic ulcers, venous ulcers, and arterial incomplete ulcers.
Shengtai Bian, Huijun Ye, Pan Wang, Changxing Li, Xutao Guo, Ming Guan, Shilun Feng   +6 more
doaj   +1 more source

“It’s made a huge difference” : recognition, rights and the personal significance of Civil Partnership [PDF]

, 2007
In this paper we map briefly some of the arguments around the meaning and significance of the introduction of Civil Partnership in England and Wales, and in this way show how contested these meanings are.
Shipman, B., Smart, C.C.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Recent Developments in Smart Food Packaging Focused on Biobased and Biodegradable Polymers

Frontiers in Sustainable Food Systems, 2021
Food packaging has a crucial function in the modern food industry. New food packaging technologies seek to meet consumers and industrial's demands. Changes related to food production, sale practices and consumers' lifestyles, along with environmental ...
Pablo R. Salgado, Luciana Di Giorgio, Yanina S. Musso, Adriana N. Mauri   +3 more
doaj   +1 more source

Smart textiles to promote multidisciplinary stem training [PDF]

, 2019
Smart textiles consist of multi-disciplinary knowledge. Disciplines such as physics, mathematics, material science or electrics is needed in order to be able to design and manufacture a smart textiles product.
BLAGA, Mirela, DIAS, Ana, DUFKOVA, Petra, GHITULEASA, Carmen, RADULESCU, Ion Razvan, SCARLAT, Razvan, STJEPANOVIC, Zoran, SURDU, Lilioara, Van Langenhove, Lieva, VISILEANU, Emilia   +9 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Future libraries with Emphasis on Smart Libraries [PDF]

تحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2010
Objective: The study intends to provide a suitable model and practical solutions for design and implementation of future digital libraries with emphasis on offering smart services Methods: Content analysis was used to collect, extract and analyze the ...
M Dilmaqani, N Naghshineh, ali moeini
doaj  

SMART MOBILITY IN SMART CITIES

Libro de Actas CIT2016. XII Congreso de Ingeniería del Transporte, 2016
Cities are currently undergoing a transformation into the Smart concept, like Smartphones or SmartTV. Many initiatives are being developed in the framework of the Smart Cities projects, however, there is a lack of consistent indicators and methodologies to assess, finance, prioritize and implement this kind of projects.
Moreno Alonso, Concepción, Baucells Aletà, Neus, Arce Ruiz, Rosa María   +2 more
openaire   +5 more sources

SMART-1 Impact Ground-based campaign [PDF]

, 2007
Based on predictions of impact magnitude and cloud ejecta dynamics, we organized a SMART-1 ground-based observation campaign to perform coordinated measurements of the impact.
Albert, L., Alkalai, L., Ansari, S., Baldwin, E., Ball, A., Banerdt, B., Barbieri, C., Berezhnoy, A., Betts, B., Bhandari, N., Biver, N., Buckley, D., Buoso, M., Burchell, M., Burke, J. D., Chandrasekhar, T., Cirou, A., Colaprete, T., Cole, M., Cook, A. C., Cooke, B., Cremonese, G., Dantowitz, R., David, L., de Morais, V. M., Di Martino, M., Dighay, J.-L., Ehrenfreund, P., Erd, C., Ferri, F., Foing, B. H., Friedman, L., Goldstein, D., Gondoin, P., Graham, F., Gurvits, L., Hanslmeyer, A., Kasuga, T., Kato, M., Kawano, N., Khodachenko, M., Koschny, D., Koschny, D., Koschny, D., Krots, A., Lammer, H., Landeau-Constantin, J., Lawton, C., Lebreton, J. P., Levasseur-Regourd, A.-C., Lucey, P., Maley, P. D., Mangano, V., Marchis, F., Matsumoto, K., Meech, K., Montanes, P., Munoz, J. M. H., Ortiz, J. L., Palle, E., Reddy, V., Rossi, A., Rucker, H., Sanguy, O., Schultz, P. H., Schultz, R., Sugita, S., Svedhem, H., Talevi, M., Taylor, C., Taylor, C., Taylor, E., Tokunaga, A., Trigo-Rodriguez, J., Vaubaillon, J., Veillet, C., Vennes, S., Weyhe, B. v., Williams, S., Wood, M., Wooden, D.   +80 more
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