Results 41 to 50 of about 412,426 (268)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
SL: A Reference Smartness Level Scale for Smart Artifacts
Information, 2022 During the last two decades, many products, research projects and prototypes were announced with different characteristics and capabilities, all adopting the “smart” qualifier word.
Nuno Costa +3 more
doaj +1 more source
From smart campus to smart cities issues of the smart revolution [PDF]
2017 IEEE SmartWorld, Ubiquitous Intelligence & Computing, Advanced & Trusted Computed, Scalable Computing & Communications, Cloud & Big Data Computing, Internet of People and Smart City Innovation (SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI), 2017 With 7/10 of the population which will live in urban center by 2050, Cities face huge challenge inviting to rethink the very concept of a City. The Smart Cities concept proposes to use Information and Communication Technologies to design sustainable solutions for improving socio-ecological aspects of cities.
Verstaevel, Nicolas +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Future libraries with Emphasis on Smart Libraries [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2010 Objective: The study intends to provide a suitable model and practical solutions for design and implementation of future digital libraries with emphasis on offering smart services Methods: Content analysis was used to collect, extract and analyze the ...
M Dilmaqani, N Naghshineh, ali moeini
doaj
The EuroBiotech Journal, 2021 Silver nanoparticles (AgNPs) have been used in a variety of biomedical applications in the last two decades, including antimicrobial, anti-inflammatory, and anticancer treatments.
Kahraman Tuğba +6 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Project activities as a factor of professional well‐being
Векторы благополучия: экономика и социумToday, project‐based teaching methods are actively developing in higher education. This format is a key tool for developing students' practical skills and professional competencies. This article presents the experience of training undergraduate students,
A.B. Zhdanova +3 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source