Results 41 to 50 of about 917,217 (248)
Antibacterial hydrogel: The sniper of chronic wounds
BMEMatChronic wounds are wounds that are difficult to heal or do not follow the normal healing process. These include pressure ulcers, diabetic ulcers, venous ulcers, and arterial incomplete ulcers.
Shengtai Bian +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Recent Developments in Smart Food Packaging Focused on Biobased and Biodegradable Polymers
Frontiers in Sustainable Food Systems, 2021 Food packaging has a crucial function in the modern food industry. New food packaging technologies seek to meet consumers and industrial's demands. Changes related to food production, sale practices and consumers' lifestyles, along with environmental ...
Pablo R. Salgado +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Future libraries with Emphasis on Smart Libraries [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2010 Objective: The study intends to provide a suitable model and practical solutions for design and implementation of future digital libraries with emphasis on offering smart services Methods: Content analysis was used to collect, extract and analyze the ...
M Dilmaqani, N Naghshineh, ali moeini
doaj
SL: A Reference Smartness Level Scale for Smart Artifacts
Information, 2022 During the last two decades, many products, research projects and prototypes were announced with different characteristics and capabilities, all adopting the “smart” qualifier word.
Nuno Costa +3 more
doaj +1 more source
Why aren't we all living in Smart Homes [PDF]
, 2014 Visions of the Future, like the Jetsons cartoons, show homes which are smart and able to control household appliances, to make living easier and more comfortable.
Suppers, Joris, Apperley, Mark
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source