This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Deep learning-based methodology for vulnerability detection in smart contracts. [PDF]
Wang Z +5 more
europepmc +1 more source
Third Party Certification of Agri-Food Supply Chain Using Smart Contracts and Blockchain Tokens. [PDF]
Dos Santos RB, Torrisi NM, Pantoni RP.
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Taxonomic insights into ethereum smart contracts by linking application categories to security vulnerabilities. [PDF]
Ortu M +4 more
europepmc +1 more source
A novel framework of collaborative early warning for COVID-19 based on blockchain and smart contracts. [PDF]
Ouyang L, Yuan Y, Cao Y, Wang FY.
europepmc +1 more source
This study shows that a local, data‐driven AI model can accurately predict diverse optical and chiroptical properties of [6]helicenes using information from close structural neighbours. Combined with genetic algorithms, it enables inverse design for tailored properties, establishing practical structure–property rules for efficient molecular discovery ...
Rafael G. Uceda +8 more
wiley +1 more source
Patient-centric federated learning: automating meaningful consent to health data sharing with smart contracts. [PDF]
Kostick-Quenet KM +3 more
europepmc +1 more source
Validation of Architecture Effectiveness for the Continuous Monitoring of File Integrity Stored in the Cloud Using Blockchain and Smart Contracts. [PDF]
Pinheiro A +3 more
europepmc +1 more source

