Results 41 to 50 of about 59,627 (257)
BMC Pharmacology and Toxicology, 2021 Background Recently, the development of nanocarriers and the improvement of their biochemical properties have became of great importance. Single-walled carbon nanotubes (SWCNT) have many applications in drug delivery systems (DDS) as a common carbon ...
Mohammad Dahri +3 more
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Pharmaceutics, 2022 Smart nanoexosomes are nanosized structures enclosed in lipid bilayers that are structurally similar to the viruses released by a variety of cells, including the cells lining the respiratory system. Of particular importance, the interaction between smart
Seyyed Mojtaba Mousavi +8 more
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A Smart RFID Device for Drugs Administration [PDF]
Pharmaceutica Analytica Acta, 2012 Abstract In this work a device is described that can be used in hospitals to lower the risk of Adverse Drug Events (ADE) due to the incorrect link between patients and drugs. The device is a container that can be handled by the patient himself of by the caregivers.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Focus on Cognitive Enhancement: A Narrative Overview of Nootropics and “Smart Drug” Use and Misuse
BiologyWhilst “nootropics” are meant to treat a range of medical disorder-related cognitive impairments, the typically healthy “smart drugs” user ingests a range of drugs/molecules to achieve improved mental performance.
Fabrizio Schifano +6 more
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Smart polymers in nasal drug delivery
Indian Journal of Pharmaceutical Sciences, 2015 Nasal drug delivery has now been recognized as a promising route for drug delivery due to its capability of transporting a drug to systemic circulation and central nervous system. Though nasal mucosa offers improved bioavailability and quick onset of action of the drug, main disadvantage associated with nasal drug delivery is mucocilliary clearance due
Ankita, Chonkar, Usha, Nayak, N, Udupa
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
PharmaceuticalsBackground: Osteoarthritis (OA) is a degenerative joint disease characterized by extracellular matrix (ECM) breakdown, inflammation, and pain-associated functional impairment.
DongHoon Lee +7 more
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Asian Journal of Medical Sciences, 2016 Background: Pneumonia severity assessment is an essential initial step in the evaluation of patients with community acquired pneumonia. Many validated severity assessment tools were designed for use in this setting.
Doha Rasheedy
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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