Results 51 to 60 of about 3,662,292 (282)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Shape memory alloy actuators for active disassembly using ‘smart’ materials of consumer electronic products [PDF]

, 2002
This paper reports the preliminary to current development of Shape Memory Alloy (SMA) actuators within their application in ‘Active Disassembly using Smart Materials’ (ADSM).
Jones, N, Billett, EH, Harrison, DJ, Chiodo, JD   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

In Vitro and In Silico Evaluations of Boswellia carterii Resin Dermocosmetic Activities

Cosmetics, 2022
Boswellia carterii is a plant species belonging to the Burseraceae family. It grows up in trees or shrubs, and it is known for producing an aromatic resin commonly named frankincense or olibanum.
Sohaib Hourfane, Hicham Mechqoq, Fatima Errajouani, João Miguel Rocha, Noureddine El Aouad   +4 more
doaj   +1 more source

Realizing Networks of Proactive Smart Products [PDF]

, 2012
The sheer complexity and number of functionalities embedded in many everyday devices already exceed the ability of most users to learn how to use them effectively. An approach to tackle this problem is to introduce ‘smart’ capabilities in technical products, to enable them to proactively assist and co-operate with humans and other products.
Mathieu d'Aquin, Enrico Motta, Andriy Nikolov, Keerthi Thomas   +3 more
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Correlation analysis between artemisinin and its derivative contents and trichome characteristics from different Artemisia species

Applied Biological Chemistry
Artemisia species have significant commercial, medical, and economic value and are widely used in the traditional medicine and pharmaceutical industries. Artemisinin, a powerful antimalarial agent, is an important pharmaceutical metabolite that primarily
Yun Ji Park, To Quyen Truong, Yeong Bin Choi, Phuong Kim Huynh, Jinyoung Moon, Song Yi Koo, Hyoung Seok Kim, Sang Min Kim   +7 more
doaj   +1 more source

Services on Platform Ecosystems in the Smart Home 2.0 Era: Elements Influencing Consumers’ Value Perception for Smart Home Products

Sensors, 2021
Recently, smart home products have shown signs of rapid development and increasing awareness of smart home platforms. In order to make smart home enterprises enter the era of Smart Home 2.0, it is necessary to consider the elements related to smart home ...
Ruiyang Tang, Yuki Inoue
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Development and application of a high-performance liquid chromatography diode-array detection (HPLC–DAD) method for the simultaneous quantification of phenolic compounds in the aerial part of Glehnia littoralis

Applied Biological Chemistry
Glehnia littoralis, a medicinal herb employed in traditional practices for alleviating fatigue, cough, and a dry throat, is recognized for its beneficial properties due to a diverse array of active compounds found in its extracts.
Yun Ji Park, Yeong Bin Choi, Sang-Bin Oh, Jinyoung Moon, To Quyen Truong, Phuong Kim Huynh, Sang Min Kim   +6 more
doaj   +1 more source