Results 41 to 50 of about 825,827 (303)

Challenges and complexities in application of LCA approaches in the case of ICT for a sustainable future [PDF]

, 2014
In this work, three of many ICT-specific challenges of LCA are discussed. First, the inconsistency versus uncertainty is reviewed with regard to the meta-technological nature of ICT. As an example, the semiconductor technologies are used to highlight the
Cheriet, Mohamed, Dandres, Thomas, Lemieux, Yves, Moghaddam, Fereydoun Farrahi, Moghaddam, Reza Farrahi, Samson, Réjean   +5 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Services on Platform Ecosystems in the Smart Home 2.0 Era: Elements Influencing Consumers’ Value Perception for Smart Home Products

Sensors, 2021
Recently, smart home products have shown signs of rapid development and increasing awareness of smart home platforms. In order to make smart home enterprises enter the era of Smart Home 2.0, it is necessary to consider the elements related to smart home ...
Ruiyang Tang, Yuki Inoue
doaj   +1 more source

Smart Integration of Energy Production [PDF]

Linköping Electronic Conference Proceedings, 2017
Abstract Heat is primarily important in the world’s total energy consumption and especially, peak loads and seasonal variations result in problems which are difficult to efficiently come up with electricity networks. Renewable energy sources bring important new possibilities, especially for the heat energy.
openaire   +2 more sources

Supporting Springer Nature Editors by means of Semantic Technologies [PDF]

, 2017
The Open University and Springer Nature have been collaborating since 2015 in the development of an array of semantically-enhanced solutions supporting editors in i) classifying proceedings and other editorial products with respect to the relevant ...
Birukou, Aliaksandr, Motta, Enrico, Osborne, Francesco, Salatino, Angelo, Thanapalasingam, Thiviyan   +4 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Correlation analysis between artemisinin and its derivative contents and trichome characteristics from different Artemisia species

Applied Biological Chemistry
Artemisia species have significant commercial, medical, and economic value and are widely used in the traditional medicine and pharmaceutical industries. Artemisinin, a powerful antimalarial agent, is an important pharmaceutical metabolite that primarily
Yun Ji Park, To Quyen Truong, Yeong Bin Choi, Phuong Kim Huynh, Jinyoung Moon, Song Yi Koo, Hyoung Seok Kim, Sang Min Kim   +7 more
doaj   +1 more source

100 years of microbial electricity production : three concepts for the future [PDF]

, 2012
Bioelectrochemical systems (BES) have been explored according to three main concepts: to produce energy from organic substrates, to generate products and to provide specific environmental services.
Arends, Jan, Verstraete, Willy
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Development and application of a high-performance liquid chromatography diode-array detection (HPLC–DAD) method for the simultaneous quantification of phenolic compounds in the aerial part of Glehnia littoralis

Applied Biological Chemistry
Glehnia littoralis, a medicinal herb employed in traditional practices for alleviating fatigue, cough, and a dry throat, is recognized for its beneficial properties due to a diverse array of active compounds found in its extracts.
Yun Ji Park, Yeong Bin Choi, Sang-Bin Oh, Jinyoung Moon, To Quyen Truong, Phuong Kim Huynh, Sang Min Kim   +6 more
doaj   +1 more source