Results 41 to 50 of about 1,170,344 (298)

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Smart Active Vibration Control System of a Rotary Structure Using Piezoelectric Materials

Sensors, 2022
A smart active vibration control (AVC) system containing piezoelectric (PZT) actuators, jointly with a linear quadratic regulator (LQR) controller, is proposed in this article to control transverse deflections of a wind turbine (WT) blade.
Ali Hashemi, Jinwoo Jang, Shahrokh Hosseini-Hashemi   +2 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Wind-Speed-Adaptive Resonant Piezoelectric Energy Harvester for Offshore Wind Energy Collection

Sensors
This paper proposes a wind-speed-adaptive resonant piezoelectric energy harvester for offshore wind energy collection (A-PEH). The device incorporates a coil spring structure, which sets the maximum threshold of the output rotational frequency, allowing ...
Weijian Wu, Zhen Pan, Jiangtao Zhou, Yingting Wang, Jijie Ma, Jianping Li, Yili Hu, Jianming Wen, Xiaolin Wang   +8 more
doaj   +1 more source

An artificial neural network model for multi-flexoelectric actuation of Plates

International Journal of Smart and Nano Materials, 2022
Flexoelectric effect can be used to design actuators to control engineering structures including beams, plates, and shells. Multiple flexoelectric actuators method has the advantage of less stress concentration and better control effect, but the mode ...
Mu Fan, Pengcheng Yu, Zhongmin Xiao
doaj   +1 more source

Smart data structures [PDF]

Proceedings of the 8th ACM international conference on Autonomic computing, 2011
As multicores become prevalent, the complexity of programming is skyrocketing. One major difficulty is efficiently orchestrating collaboration among threads through shared data structures. Unfortunately, choosing and hand-tuning data structure algorithms to get good performance across a variety of machines and inputs is a herculean task to add to the ...
Eastep, Jonathan Michael, Wingate, David, Agarwal, Anant   +2 more
openaire   +3 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Wind-Wave Synergistic Triboelectric Nanogenerator: Performance Evaluation Test and Potential Applications in Offshore Areas

Micromachines
Triboelectric nanogenerators (TENGs) can effectively collect low-frequency, disordered mechanical energy and are therefore widely studied in the field of ocean energy collection. Most of the rotary TENGs studied so far tend to have insufficient rotation,
Zhen Pan, Weijian Wu, Jiangtao Zhou, Yili Hu, Jianping Li, Yingting Wang, Jijie Ma, Jianming Wen   +7 more
doaj   +1 more source