Results 41 to 50 of about 7,891 (262)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Active Hybrid Solid State Transformer Based on Multi-Level Converter Using SiC MOSFET
Energies, 2018 As the types of loads have been diversified and demand has increased, conventional distribution transformers are difficult to maintain the constant voltage against voltage drop along with distance, grid voltage swell/sag, and various loads.
Chun-gi Yun, Younghoon Cho
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Energies, 2022 After the massive integration of distributed energy resources, energy storage systems and the charging stations of electric vehicles, it has become very difficult to implement an efficient grid energy management system regarding the unmanageable behavior
Oussama Laayati +6 more
doaj +1 more source
Power distribution transformers are key infrastructural elements whose operational failure introduces network instability, high repair liabilities, and customer power disruptions. Standard manual maintenance schemes cannot prevent rapid failures caused by overloading and unexpected thermal spikes in real time.
Jaydip Shirsath +4 more
openaire +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
MathematicsHybrid Distribution Transformers (HDTs) offer a compelling alternative to traditional low-frequency transformers (LFTs), providing auxiliary services in addition to standard functionalities.
Esteban I. Marciel +5 more
doaj +1 more source
Smart Transformations: The Evolution of Choice Principles
CoRR, 2015 Evolutionary game theory classically investigates which behavioral patterns are evolutionarily successful in a single game. More recently, a number of contributions have studied the evolution of preferences instead: which subjective conceptualizations of a game's payoffs give rise to evolutionarily successful behavior in a single game. Here, we want to
Paolo Galeazzi, Michael Franke
openaire +3 more sources
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source