Results 121 to 130 of about 221,167 (311)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

KONTRIBUSI DAYA LEDAK LENGAN DAN KELENTUKAN TOGOK KE BELAKANG TERHADAP KEMAMPUAN SMASH DALAM PERMAINAN BULUTANGKIS PADA ATLET BKMF BULUTANGKIS FIK UNM [PDF]

, 2015
: Smash is one form of attack that can killthe opponent's defense as well as to obtain the value or point. In the game of badminton, smash is one technique that plays an important role, failed and successful team in the game or match is determined by the
H., Herman
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Faktor Anthropometri Dan Fisik Dominan Penentu Ketepatan Smash Bulutangkis pada Club PB. FIK Uncen

Multilateral: Jurnal Pendidikan Jasmani dan Olahraga
Badminton adalah olahraga yang populer di Indonesia, termasuk di Kota Jayapura, di mana PB. FIK Uncen berperan aktif dalam pembinaan atlet berbakat. Pencapaian prestasi dalam bulu tangkis sangat bergantung pada penguasaan teknik, dengan salah satu teknik
Evi Sinaga, Junalia Muhammad, Nasruddin Nasruddin, Yulia Cinta Ramadhani, Miftah Fariz Prima Putra   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Pengaruh Kemampuan Fisik Terhadap Keterampilan Smash Dalam Cabang Olahraga Bulutangkis Anggota Club Bulutangkis ICLI Gowata Sungguminasa Kabupaten Gowa [PDF]

, 2017
Penelitian ini adalah jenis penelitian Ex Post Facto yang bertujuan untuk mengetahui: (1) Apakah ada pengaruh fleksibitas pergelangan tangan terhadap keterampilam smash dalam olahraga bulutangkis.
WAHAB, WAIS AULIYAH
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Pengaruh Metode Latihan dan Power Lengan Terhadap Kemampuan Smash Bulutangkis [PDF]

, 2013
Tujuan penelitian ini untuk mengungkapkan: (1) perbedaan pengaruh metode drill dan bermain terhadap peningkatan kemampuan smash bulutangkis, (2) perbedaan peningkatan kemampuan smash bulutangkis antara metode drill atlet yang memiliki power otot lengan ...
Prayadi, Heri Yogo
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source