Results 91 to 100 of about 99,233 (150)

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Genetic inactivation of the phosphatase activity of soluble epoxide hydrolase prevents the development of pulmonary hypertension in rats, partly through upregulation of SIRT3 expression and decreased cell proliferation and apoptosis‐related proteins. Targeting sEH‐P emerges as a promising therapeutic strategy for pulmonary hypertension.
Matthieu Leuillier, Mustapha Chelgham, Hind Messaoudi, Ly Tu, Severine Ménoret, Raphaël Thuillet, Déborah Groussard, Felix F. Lillich, Mina Ottaviani, Lionel Nicol, Paul Mulder, Marc Humbert, Vincent Richard, Ignacio Anegon, Christophe Morisseau, Ewgenij Proschak, Christophe Guignabert, Jérémy Bellien   +17 more
wiley   +1 more source

Polydatin Protects Against the Formation of PPE‐Induced Abdominal Aortic Aneurysms in Mice by Activating Nuclear Factor Erythroid 2‐Related Factor 2

Drug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Sudden death resulting from abdominal aortic aneurysm (AAA) rupture is a highly fatal cardiovascular condition. There remains an urgent need to identify innovative therapeutic strategies capable of decelerating AAA progression and rupture. Although polydatin (PLD) has been consistently shown to exert potent anti‐inflammatory effects in diverse
Zikang Liu, Jinyi Zhu, Qian Zhou, Haiyun Qian, Fenghe Cui   +4 more
wiley   +1 more source

Position Control of Electro‐Hydraulic Actuator System With Disturbances Compensation

Energy Science &Engineering, Volume 14, Issue 2, Page 831-842, February 2026.
A novel output feedback controller based on global fast terminal sliding mode with disturbances rejection to achieve accurate position tracking control for electro‐hydraulic cylinder system, which shows the great control potential of the designed output feedback controller during the start‐up and operation of the electro‐hydraulic actuator system ...
Yunfei Wang, Haigang Ding, Jiaxiang Man
wiley   +1 more source

Improving the Characteristics of the Direct FOC Strategy in DFIG‐Based Wind Turbine Systems Using FOIDD and FOPD Controllers

Energy Science &Engineering, Volume 14, Issue 2, Page 999-1021, February 2026.
This study presents a new control strategy for doubly fed induction generator (DFIG) wind turbine systems to overcome the limitations of traditional direct field control using proportional‐integral (DFOC‐PI) regulators, which are sensitive to coefficient changes and lead to low power quality.
Hamza Gasmi, Habib Benbouhenni, Z. M. S. Elbarary, Ilhami Colak, Tahar Tafticht, Salman Arafath Mohammed   +5 more
wiley   +1 more source

Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response

MedComm, Volume 7, Issue 2, February 2026.
Increased miR‐3163 targets NUDT21, reducing CPSF5 levels and driving APA dysregulation. This results in 3′UTR shortening of CBFB, which stabilizes RUNX1 and promotes smooth muscle proliferation. PTGER3, is also shortened amplifying hypoxia‐induced RVSP. Together, these pathways contribute to vascular remodeling in PH. Image Created in https://BioRender.
Scott D. Collum, Lisha Zhu, Tingting W. Mills, Rene Girard, Jamie Tran, Tinne C. J. Mertens, Cory Wilson, Nancy Wareing, Erik E. Suarez, Howard J. Huang, Rahat Hussain, Bindu Akkanti, Wenjin J. Zheng, Hari K. Yalamanchili, Bela Patel, Eric J. Wagner, Sandeep Agarwal, Harry Karmouty‐Quintana   +17 more
wiley   +1 more source

Psychometric Properties of the Traditional Chinese Version of the Interprofessional Collaborative Competency Attainment Survey

Research in Nursing &Health, Volume 49, Issue 1, Page 87-96, February 2026.
ABSTRACT This study aimed to develop and validate the Traditional Chinese version of the Interprofessional Collaborative Competency Attainment Survey (TC‐ICCAS), a culturally sensitive tool for assessing interprofessional education (IPE) competencies in Taiwan's hierarchical healthcare system.
Yawen Lee, Chihlung Chiang, Yungsung Wen, Chinyi Huang, Hsintzu Li, Chihhao Lin   +5 more
wiley   +1 more source

N2 fixation is linked to the ability to encroach in African savanna trees

Functional Ecology, Volume 40, Issue 2, Page 517-533, February 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Encroachment is a globally ubiquitous phenomenon, characterised by increasing indigenous tree densities in savanna and grassland. Encroachment has been attributed to rising atmospheric CO2 concentrations fertilising tree growth and shifting the competitive balance ...
Elizabeth M. Telford, Kimberley Simpson, Lorna Street, Emily Fletcher, Richard Carkeek, Russell B. Dixon, Katie J. Field, Emma Jones, Sarah L. Raubenheimer, Edith Singini, Brad Ripley, Colin P. Osborne, Caroline E. R. Lehmann   +12 more
wiley   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Impact of Growth Hormone Treatment in Children From an Extended Family With ACAN ‐Related Short Stature

Clinical Genetics, Volume 109, Issue 2, Page 374-379, February 2026.
This study evaluated growth hormone (GH) therapy in children from an extended family with genetically confirmed ACAN‐related short stature. While GH treatment improved growth velocity, the response varied among individuals, and its long‐term impact on final adult height remains to be determined.
Einat Shalev‐Goldman, Ayman Asaly, Hadas Ityel, Ben Pode‐Shakked, Dalit Modan‐Moses, Yael Levy‐Shraga   +5 more
wiley   +1 more source

Climate Change Challenges Grey Wolf Resilience: Insights From Dental Microwear

Ecology Letters, Volume 29, Issue 2, February 2026.
We investigate dietary plasticity in European grey wolves across interglacial periods using dental microwear texture analysis. Enhanced durophagy is associated with warm climates in both modern Polish and British Pleistocene wolves, indicating deep‐time behavioural flexibility.
Amanda A. Burtt, Neil F. Adams, Sabina Nowak, Robert W. Mysłajek, Michal Figura, Mark A. Purnell, Angela L. Lamb, Danielle C. Schreve   +7 more
wiley   +1 more source