Results 71 to 80 of about 536,687 (331)

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

Advanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria, Cristina Iglesias, Sascha Jung, Javier Arcos Hodar, Ruben Nogueiras, Antonio del Sol   +5 more
wiley   +1 more source

Preoperative nutrition intervention program increases cleft surgery eligibility in the low- and middle-income country setting

BMC Nutrition
Background Children with cleft lip and/or palate (CL/P) are highly susceptible to malnutrition, which may restrict surgery eligibility and delay repair.
Devon O’Brien, Meenakshi Mitra, Mallika Jadly, Allyn Auslander, Abhishek Sengupta   +4 more
doaj   +1 more source

Q‐GEM: Quantum Chemistry Knowledge Fusion Geometry‐Enhanced Molecular Representation for Property Prediction

Advanced Science, EarlyView.
This work introduces E‐GeoGNN, a graph neural network framework that systematically encodes molecular structural information through three hierarchical correlation graphs: atom‐bond graph, bond‐angle graph, and angle‐dihedral graph. By incorporating quantum and geometric dual‐scale self‐supervised pretraining, Q‐GEM is proposed, a novel molecular ...
Zhijiang Yang, Liangliang Wang, Tengxin Huang, Yunfan Wang, Mingchi Gao, Tingjun Hou, Junjie Ding, Junhua Xiao   +7 more
wiley   +1 more source

Cap-preserving SMILE Enhancement Surgery

BMC Ophthalmology, 2018
Background Different enhancement procedures have been suggested for reduction of residual refractive errors after SMILE. The aim of this study is to evaluate an improved cap-preserving technique for enhancement after SMILE (Re-SMILE).
Ahmed N. Sedky, Sherine S. Wahba, Maged M. Roshdy, Nermeen R. Ayaad   +3 more
doaj   +1 more source

Harnessing Machine Learning to Enhance Transition State Search with Interatomic Potentials and Generative Models

Advanced Science, EarlyView.
Comprehensive evaluation of MLIPs and generative models for TS search using an end‐to‐end benchmark platform. Success rates, TS quality, and barrier prediction errors are systematically compared across models. The results reveal key performance trade‐offs and provide actionable insights for improving ML‐based transition state search and reaction ...
Qiyuan Zhao, Yunhong Han, Duo Zhang, Jiaxu Wang, Peichen Zhong, Taoyong Cui, Bangchen Yin, Yirui Cao, Haojun Jia, Chenru Duan   +9 more
wiley   +1 more source

New readout and data-acquisition system in an electron-tracking Compton camera for MeV gamma-ray astronomy (SMILE-II) [PDF]

, 2015
For MeV gamma-ray astronomy, we have developed an electron-tracking Compton camera (ETCC) as a MeV gamma-ray telescope capable of rejecting the radiation background and attaining the high sensitivity of near 1 mCrab in space. Our ETCC comprises a gaseous
Iwaki, Satoru, Kishimoto, Tetsuro, Komura, Shotaro, Kubo, Hidetoshi, Kurosawa, Shunsuke, Matsuoka, Yoshihiro, Miuchi, Kentaro, Miyamoto, Shohei, Mizumoto, Tetsuya, Mizumura, Yoshitaka, Nakamura, Kiseki, Nakamura, Shogo, Oda, Makoto, Parker, Joseph D., Sawano, Tatsuya, Sonoda, Shinya, Takada, Atsushi, Takemura, Taito, Tanimori, Toru, Tomono, Dai   +19 more
core   +2 more sources

Collaborative Uses of GenAI Tools in Project-Based Learning

Education Sciences
Artificial intelligence (AI) is forcing a dramatic transformation of the methods by which we acquire knowledge and engage in collaborative learning. Although there are several studies on how AI can support collaborative learning, there are no published ...
Maria Perifanou, Anastasios A. Economides   +1 more
doaj   +1 more source

Mandelbrot and the Smile

Credit and Capital Markets – Kredit und Kapital, 2009
Summary/Zusammenfassung Mandelbrot and the Smile It is a well-documented empirical fact that index option prices systematically differ from Black-Scholes prices. However, previous research provides inconclusive results whether the observed volatility smile could be explained by a discretetime dynamic model of stock returns with skewed, leptokurtic ...
openaire   +6 more sources

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

Advanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin, Chang Che, Aimin Jiang, Chang Qi, Antonino Glaviano, Zhijie Zhao, Zhirou Zhang, Zaoqu Liu, Ziyao Zhou, Quan Cheng, Shuofeng Yuan, Peng Luo   +11 more
wiley   +1 more source