Results 121 to 130 of about 4,313,154 (287)

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha   +6 more
wiley   +1 more source

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li   +3 more
wiley   +1 more source

FX Smile in the Heston Model [PDF]

open access: yes
The Heston model stands out from the class of stochastic volatility (SV) models mainly for two reasons. Firstly, the process for the volatility is nonnegative and mean-reverting, which is what we observe in the markets.
Rafal Weron   +3 more
core  

The Japanese Adaptation of the Reading the Mind in Films Test: Differentiating Autism Spectrum Disorder From Depression Using an Ecologically Valid Social Cognitive Task

open access: yesAutism Research, EarlyView.
ABSTRACT Cognitive tests that reflect the complexity of real‐world social interactions are essential for autism spectrum disorder (ASD)‐related clinical assessment and research. This study developed and adapted a Japanese version of the Reading the Mind in Films (RMF) test, which assesses mind‐reading ability through dynamic, multisensory, and context ...
Sayaka Kawakami   +3 more
wiley   +1 more source

Rub Off your Wrinkles with a Smile

open access: yes, 1923
First Line: I see a tear in your eye my dearFirst Line of Chorus: Rub off your wrinkles with a smile, dearKey: E Flat ...

core  

Identification of Putative Cellulose Synthase Gene xcsA2 Required for c‐di‐GMP‐Induced Biofilm Formation and Cell Aggregation in Synechococcus elongatus PCC 7942

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Synechococcus elongatus PCC 7942 is a widely used model cyanobacterium for diverse research fields and for bioproduction applications owing to its ease of cultivation, genetic modification, and ability to fix CO2. We found that a laboratory strain of S. elongatus PCC 7942 expressing the ydeH gene from E.
Chihiro C. Yamaguchi   +3 more
wiley   +1 more source

Analysis of the smile photograph.

open access: yes, 2006
Optimal facial esthetics is one of the objectives in orthodontic treatment and an important issue in modern society. In this context, orthodontic treatment permits individuals with dental malpositions to achieve improved dentofacial esthetics.
Gandini Júnior, Luiz Gonzaga [UNESP]   +4 more
core   +2 more sources

Just Try A Smile Or Two

open access: yes, 1923
First Line: What is the use of fretting, when trouble comes alongFirst Line of Chorus: One smile or two, when you feel blueKey: F ...

core  

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah   +8 more
wiley   +1 more source

Save a Little Sunny Smile for Me

open access: yes, 1907
First Line: Bill Jones said to his lady love, Lordy!First Line of Chorus: Honey!

core  

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