Results 61 to 70 of about 4,313,154 (287)

Balsa: A Compact Line Notation Based on SMILES

, 2022
Despite its widespread use, Simplified Molecular Input Line Entry System (SMILES) remains underspecified. The lack of a detailed specification encourages improvisation by software developers, complicates data standardization efforts, and undermines extension development. Balsa, a reformulation of SMILES, addresses these problems.
openaire   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Comparison of the Early Clinical Outcomes between Combined Small-Incision Lenticule Extraction and Collagen Cross-Linking versus SMILE for Myopia

Journal of Ophthalmology, 2016
Background. To compare the early outcome of combined SMILE and collagen crosslinking (SMILE Xtra) with SMILE. Method. Prospective, comparative interventional study of 21 eyes receiving SMILE Xtra using a low energy protocol and 32 control eyes receiving ...
Alex L. K. Ng, Tommy C. Y. Chan, George P. M. Cheng, Vishal Jhanji, Cong Ye, Victor C. P. Woo, Jimmy S. M. Lai   +6 more
doaj   +1 more source

Esthetic analysis of the smile

Brazilian Journal of Oral Sciences, 2016
This study analyzed the esthetics components of the smile, evaluating the relationship between the curve formed by the incisal line of the anterior superior teeth and the curve of the inferior lip, the touch of this incisal line on the inferior lip, the ...
Giulliana Panfiglio Soares, Thiago Assunção Valentino, Débora Alves Nunes Leite Lima, Luis Alexandre Maffei Sartini Paulillo, Frederico Augusto Peixoto Silva, José Roberto Lovadino   +5 more
doaj   +1 more source

The relationship between different levels of facial attractiveness and malocclusion perception: an eye tracking and survey study

Progress in Orthodontics, 2023
Introduction The aim of this study was to investigate the relationship between levels of facial attractiveness and the perception of different types of malocclusion.
Merve Zorlu, Hasan Camcı
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Clinical audit of an artificial intelligence (AI) empowered smile simulation system: a prospective clinical trial

Scientific Reports
Smile aesthetics is an important factor to consider during orthodontic treatment planning. The aim of the present study is to assess the predictability of Invisalign SmileView for digital AI smile simulation in comparison to actual smile treatment ...
Samar M. Adel, Yashodhan M. Bichu, Srirengalakshmi Muthuswamy Pandian, Waddah Sabouni, Chandani Shah, Nikhillesh Vaiid   +5 more
doaj   +1 more source

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

Long-term Results of Small-incision Lenticule Extraction in High Myopia

Türk Oftalmoloji Dergisi, 2016
Objectives: To evaluate two-year results of small-incision lenticule extraction (SMILE) for correction of high myopia. Materials and Methods: Forty-five eyes of 35 patients with mean spherical equivalent (SE) of -7.10±0.95 D who underwent routine SMILE ...
Yusuf Yıldırım, Cengiz Alagöz, Abdülvahit Demir, Onur Ölçücü, Mehmet Özveren, Alper Ağca, Engin Bilge Özgürhan, Ahmet Demirok   +7 more
doaj   +1 more source

Lip line in deep bite patients [PDF]

Iranian Journal of Orthodontics, 2008
Aim: The aim of modem orthodontic treatments is to improve facial esthetics as well as dental occlusion and create an attractive smile. The purpose of the present study was to assess lip line in deep bite patients in comparison to the normal situation ...
Arezoo Jahanbin, Habibollah Esmaily, Yasaman Sardari, Maryam Poosti, Mahdiyeh Kazemian   +4 more
doaj   +1 more source