Results 141 to 150 of about 2,634,989 (242)

AutoVap: An Interactive Machine Learning Tool for Predicting the Standard Enthalpy of Vaporization

open access: yesChemie Ingenieur Technik, EarlyView.
AutoVap (https://autovap.jfcaetano.com) is a web app that predicts ΔvapHm° from SMILES using an RDKit‐based ML model, giving accurate, interpretable results with uncertainty across diverse molecules. ABSTRACT This communication introduces AutoVap (https://autovap.jfcaetano.com), an interactive web application for predicting the standard molar enthalpy ...
José Ferraz‐Caetano
wiley   +1 more source

The relationship between smile attractiveness and esthetic parameters of patients with lateral agenesis treated with tooth recontouring or implants

open access: yes, 2012
Luciana Manzotti De-Marchi,1 Núbia Inocencya Pavesi Pini,2 Renata Corrêa Pascotto31Department of Dentistry, University Center of Maringá-CESUMAR, Maringá-PR/Brazil; 2Piracicaba Dental School, State University of
De-Marchi LM, Pascotto RC, Pini NI
core  

A Graph‐Based Generative Artificial Intelligence Methodology for Autocorrection of Utility‐System P&IDs

open access: yesChemie Ingenieur Technik, EarlyView.
This work explores generative AI for automated revision of Piping and Instrumentation Diagrams (P&IDs). We frame P&ID correction as a translation problem, converting attributed P&ID graphs into sequences and learning revisions with a transformer‐based model.
Lukas Schulze Balhorn   +5 more
wiley   +1 more source

Mitigating measurement error in misspecified small area models

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract In the framework of Small area estimation, we consider an area‐level model where a subset of covariates is measured with error. The extent of the error is assumed to be constant throughout the areas, and it is expressed by a scalar parameter γ$$ \gamma $$, which multiplies the deterministic covariance matrix of the estimator of the true ...
Diego Battagliese   +3 more
wiley   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata   +9 more
wiley   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang   +2 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian   +5 more
wiley   +1 more source

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