Results 41 to 50 of about 252,758 (328)

PolyLLM: polypharmacy side effect prediction via LLM-based SMILES encodings

Frontiers in Pharmacology
Polypharmacy, the concurrent use of multiple drugs, is a common approach to treating patients with complex diseases or multiple conditions. Although consuming a combination of drugs can be beneficial in some cases, it can lead to unintended drug-drug ...
Sadra Hakim, Alioune Ngom
doaj   +1 more source

Mood meter: counting smiles in the wild [PDF]

, 2012
In this study, we created and evaluated a computer vision based system that automatically encouraged, recognized and counted smiles on a college campus.
Drevo, Will, Hernandez Rivera, Javier, Hoque, Mohammed Ehasanul, Picard, Rosalind W.   +3 more
core   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Analysis of eye movements in the judgment of enjoyment and non-enjoyment smiles

Frontiers in Psychology, 2013
Enjoyment smiles are more often associated with the simultaneous presence of the Cheek raiser and Lip corner puller action units, and these units’ activation is more often symmetric.
Mélanie ePerron, Annie eRoy-Charland
doaj   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Analysis of gingival display during static and dynamic smiles in a Turkish sample: a clinical study

European Oral Research, 2022
Purpose: The aim of this study is to determine the prevalence of smile types in spontaneous smiles among a Turkish population aged 18–23 and to compare it with the prevalence of static smiles.
Özge Arifağaoğlu, Ümran Yılmaz
doaj   +1 more source

Lowering Student Loan Default Rates: What One Consortium of Historically Black Institutions Did to Succeed [PDF]

, 2010
Outlines best-practice strategies historically black colleges and universities in Texas used in the 1990s to lower student loan default rates and avoid losing federal aid, including campuswide collaboration, partnerships, and teaching financial ...
Erin Dillon, Robin V. Smiles
core  

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Towards a Universal SMILES representation - A standard method to generate canonical SMILES based on the InChI

Journal of Cheminformatics, 2012
Background There are two line notations of chemical structures that have established themselves in the field: the SMILES string and the InChI string.
O’Boyle Noel M
doaj   +1 more source

Management of internal root resorption in primary mandibular right first molar: A case report with four-year follow-up

Contemporary Pediatric Dentistry, 2021
Internal inflammatory root resorption in primary teeth is a well-known entity with unknown prevalence. The diagnosis and conservative treatment of such a lesion has perplexed practitioners for decades.
Prasad K Musale, Sneha S Kothare, Abhinav l Talekar   +2 more
doaj   +1 more source