Results 161 to 170 of about 21,785 (265)

Exploring the Potential of a Scenario-Based Approach to Early Autism Spectrum Disorder Screening. [PDF]

open access: yesPsychiatry Investig
Bong G   +7 more
europepmc   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan   +12 more
wiley   +1 more source

Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren   +13 more
wiley   +1 more source

Accessing the Levator Labii Superioris Alaeque Nasi (LLSAN) Muscle for the Treatment of Infraorbital Dimples-A Case Report. [PDF]

open access: yesJ Cosmet Dermatol
Escobar S   +7 more
europepmc   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

open access: yesEpilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni   +4 more
wiley   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam   +8 more
wiley   +1 more source

Does baseline language ability predict response to early intervention for toddlers with early signs of autism? Evidence from a caregiver-mediated program. [PDF]

open access: yesFront Hum Neurosci
Brian JA   +12 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

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