Results 31 to 40 of about 262,118 (350)

BC‐11 is a covalent TMPRSS2 fragment inhibitor that impedes SARS‐CoV‐2 host cell entry

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Drug repurposing has the potential to accelerate the discovery of TMPRSS2 inhibitors acting as COVID‐19 antivirals. In this regard, a low throughput screening led to the identification of BC‐11 as a covalent TMPRSS2 fragment inhibitor (IC50 = 1.44 µM), displaying significant SARS‐CoV‐2 entry inhibition (EC50 = 66 µM). Abstract Host cell entry of severe
Aurélien F. A. Moumbock   +3 more
wiley   +1 more source

The color of smiling: computational synaesthesia of facial expressions [PDF]

open access: yes, 2015
This note gives a preliminary account of the transcoding or rechanneling problem between different stimuli as it is of interest for the natural interaction or affective computing fields. By the consideration of a simple example, namely the color response
C Spence   +15 more
core   +2 more sources

Smiles in delta [PDF]

open access: yesarXiv, 2022
Fukasawa introduced in [Fukasawa, Math Financ, 2012] two necessary conditions for no butterfly arbitrage which require that the $d_1$ and $d_2$ functions of the Black-Scholes formula have to be decreasing. In this article we characterize the set of smiles satisfying these conditions, using the parametrization of the smile in delta.
arxiv  

Infusing Linguistic Knowledge of SMILES into Chemical Language Models [PDF]

open access: yesarXiv, 2022
The simplified molecular-input line-entry system (SMILES) is the most popular representation of chemical compounds. Therefore, many SMILES-based molecular property prediction models have been developed. In particular, transformer-based models show promising performance because the model utilizes a massive chemical dataset for self-supervised learning ...
arxiv  

Smile: A review

open access: yesJournal of Pharmacy And Bioallied Sciences, 2015
"Beauty is in the mind of the beholder, each mind perceives a different beauty" famously said by writer Margeret Wolfe Hungerford. A beautiful smile is a gateway to the world. The aim of this article was to identify the criteria for designing the perfect smile.
W. S. Manjula   +4 more
openaire   +4 more sources

Upper Lip Asymmetry During Smiling: An Analysis Using Three-Dimensional Images

open access: yesTurkish Journal of Orthodontics, 2018
Objective:The aim of this study was to use three-dimensional images to determine the presence of upper lip asymmetry at rest and during smiling in a group of individuals with no history of orthodontics or facial cosmetic surgery.MethodsStandardized three-
Andrew Mathis   +4 more
doaj   +1 more source

Tip Droop Prevention in Rhinoplasty: Dynamic Effect of Strut Graft on Smiling versus Depressor Muscle Release

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Background:. Aesthetic rhinoplasty is one of the most challenging procedures performed by aesthetic surgeons. Tip droop, especially on smiling, may not be noted by the surgeon postoperatively but can be concerning to patients. Our aim was to determine if
Chevonne Brady, MRCS   +2 more
doaj   +1 more source

Systematic review of antitumour efficacy and mechanism of metformin activity in prostate cancer models

open access: yesBJUI Compass, Volume 4, Issue 1, Page 44-58, January 2023., 2023
Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting.
Nan Fang Wang   +3 more
wiley   +1 more source

Educators' positive practices with refugee pupils at two schools in England

open access: yesBritish Educational Research Journal, Volume 48, Issue 6, Page 1125-1144, December 2022., 2022
Abstract Extensive evidence indicates that education is an integral part of the settling in process for refugee and asylum‐seeking children. Furthermore, it has been suggested that positive teaching practice with refugee pupils should be asset‐based and holistic in nature. The present study examines educators' positive practices with refugee pupils and
Caitlin M. Prentice
wiley   +1 more source

CIRURGIA PERIODONTAL RESSECTIVA VALORIZANDO O SORRISO GENGIVAL: RELATO DE CASO CLÍNICO

open access: yesColloquium Vitae, 2012
Currently, to meet the growing expectations of patients regarding oral aesthetics must be prepared to provide, to the extent possible, the aesthetic results desired.
Sheyla Adriane Rodrigues de Oliveira   +1 more
doaj   +1 more source

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