Results 71 to 80 of about 36,435 (290)

The smile.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971
No ...
openaire   +3 more sources

Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa, Kenjiro Kosaki, Toshiki Takenouchi   +2 more
wiley   +1 more source

Mitigating Molecular Aggregation in Drug Discovery With Predictive Insights From Explainable AI

Angewandte Chemie, EarlyView.
In this work, MEGAN, our explainable AI model, is applied to predict small colloidally aggregating molecules (SCAMs), a significant source of false positives in drug discovery. MEGAN provides interpretable predictions and proposes structurally similar, non‐aggregating alternative molecules.
Hunter Sturm, Jonas Teufel, Kaitlin A. Isfeld, Pascal Friederich, Rebecca L. Davis   +4 more
wiley   +2 more sources

Examining the effect of active participation on the TPACK knowledge of mathematics educators in a teaching mathematics with technology MOOC

International Journal of Educational Research Open
As the demand for incorporating educational technologies into the mathematics teaching curriculum rises, there is an increasing need for teachers to cultivate the competencies and skills essential for the effective integration of technology into their ...
James Smiling, Karen Hollebrands
doaj  

Age-related changes in the Brazilian woman’s smile

Brazilian Oral Research, 2016
The aim of this research was to evaluate age-related changes in the smile of Brazilian women. The sample consisted of 249 Brazilian women who had not undergone previous orthodontic treatment or facial surgery.
Luiza Nayara Almeida Lyra CORREIA, Silvia Augusta Braga REIS, Ana Claudia de Castro Ferreira CONTI, Leopoldino CAPELOZZA FILHO, Renata Rodrigues ALMEIDA-PEDRIN   +4 more
doaj   +1 more source

Exploring Oral Health Related Quality of Life in Rett Syndrome Using Directed Content Analysis

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT No validated oral health‐related quality of life (OHRQOL) instrument currently exists for those with severe intellectual and developmental disabilities and who communicate non‐verbally. This qualitative study aimed to explore the domains that were important to the oral health‐related quality of life in individuals with Rett syndrome (RTT).
Yvonne Yee Lok Lai, Jenny Anne Downs, Helen Margaret Leonard, Laurence James Walsh, Sobia Zafar   +4 more
wiley   +1 more source

Deep Supramolecular Language Processing for Co‐Crystal Prediction

Angewandte Chemie, EarlyView.
DeepCocrystal is a deep learning model that predicts co‐crystal formation by learning supramolecular interactions from molecular string representations. It achieves high accuracy, estimates uncertainty, and offers interpretable insights into its predictions. Validated prospectively, DeepCocrystal discovered novel diflunisal co‐crystals and is available
Rebecca Birolo, Rıza Özçelik, Andrea Aramini, Roberto Gobetto, Michele R. Chierotti, Francesca Grisoni   +5 more
wiley   +2 more sources

Smile Arc in Palestinian Adolesants

Turkish Journal of Orthodontics, 2009
Smile Arc is good indicator of dentolabial harmony and attractiveness. The number of teeth displayed has an impact on smiling. Smiles which show first molar to first molar are judged the most attractive.
Ma'n. M. N Mahfouz, Emad Hussein, Alev Aksoy-Doğan   +2 more
doaj   +1 more source

Patient With Prolidase Deficiency due to an Homozygous PEPD Variant, Induced by Paternal Uniparental Isodisomy of Chromosome 19

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive pathogenic variants in both alleles. Additionally, depending on the mechanisms by which UPD occurs, mosaic aneuploidies may
Marta Carreño‐Hidalgo, Raquel Muñoz‐Siles, Vanesa López‐González, Lidia Carreño‐Gago, Lluís Armengol Dulcet   +4 more
wiley   +1 more source

Advancing Sulfinyl Radical Chemistry: An Asymmetric Smiles Rearrangement with Chiral Sulfoxides

Angewandte Chemie, EarlyView.
A visible‐light‐driven, asymmetric sulfinyl‐Smiles rearrangement enables the enantioselective trifunctionalization of chiral sulfoxides via radical addition, 1,5‐aryl migration, and sulfinyl radical interception. By tuning the redox potentials of key components, this cascade forms two C─C and one C─S bond in a single step, yielding enantioenriched ...
Yawen Hu, Till Schreyer, Cristina Nevado
wiley   +2 more sources