Results 291 to 300 of about 105,970 (372)

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen   +18 more
wiley   +1 more source

Psychometric evaluation of a trans‐addiction craving questionnaire: The Craving Assessment Scale for Behavioral Addictions and Substance‐use Disorders (CASBAS)

open access: yesAddiction, Volume 121, Issue 2, Page 400-412, February 2026.
Abstract Background and aims Craving is a central construct across different kinds of addictive disorders, but craving assessments are highly heterogeneous. Our aim was to develop a valid, standardized and short scale for assessing subjective feelings of acute craving for different substances and addictive behaviors using the same set of items.
Stephanie Antons   +6 more
wiley   +1 more source

Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms

open access: yesAllergy, Volume 81, Issue 2, Page 427-453, February 2026.
The Allergic Rhinitis and its Impact on Asthma (ARIA) group is working on the 2024–2025 update of its guidelines for the management of allergic rhinitis (ARIA 2024–2025). The ARIA 2024–2025‐EAACI guidelines will follow GRADE methodology and will incorporate evidence from different sources, including systematic reviews and meta‐analyses, mHealth data ...
Jean Bousquet   +230 more
wiley   +1 more source

Identification of CD320, SLC44A1 and TNFRSF13B as potential novel therapeutic targets for CAR T-cell therapy in multiple myeloma. [PDF]

open access: yesFront Med (Lausanne)
Garofano F   +7 more
europepmc   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

open access: yesCancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki   +3 more
wiley   +1 more source

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