Results 31 to 40 of about 293,142 (297)
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Mind the Gap: Disparities in Cigarette Smoking in Canada
Tobacco Use Insights, 2019 Objectives: The Government of Canada has proposed an ‘endgame’ target for cigarette smoking that aims to reduce prevalence below 5% by 2035. To meet this difficult goal, it will be necessary to identify populations where interventions will (1) have the ...
Michael Chaiton, Cynthia Callard
doaj +1 more source
Cardiovascular Innovations and Applications, 2016 Objective: To review the literature on associations between cardiovascular diseases and tobacco use, including recent trends in smoking behaviors and clinical approaches for cessation of smoking. Methods: A literature review of recent scientific findings for smoking and cardiovascular diseases and recommendations for obtaining cessation.
openaire +3 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Fire, 2019 Poor air quality arising from prescribed and wildfire smoke emissions poses threats to human health and therefore must be taken into account for the planning and implementation of prescribed burns for reducing contemporary fuel loading and other ...
Kellen N. Nelson +7 more
doaj +1 more source
Rumores, 2009 <p style="text-align: justify;"><span style="font-size: 12px; font-family: Arial;">Quando vemos um filme não esperamos que nossas ações interfiram na narrativa, no entanto, nas mídias digitais podemos nos defrontar com situações em que a narrativa é alterada pela nossa participação.
openaire +4 more sources
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Multi-Sensor Person Following in Low-Visibility Scenarios
Sensors, 2010 Person following with mobile robots has traditionally been an important research topic. It has been solved, in most cases, by the use of machine vision or laser rangefinders.
Javier Pérez +4 more
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
GeoHealth, 2019 Emissions of particulate matter from fires associated with land management practices in Indonesia contribute to regional air pollution and mortality. We assess the public health benefits in Indonesia, Malaysia, and Singapore from policies to reduce fires
Miriam E. Marlier +10 more
doaj +1 more source