Results 171 to 180 of about 66,888 (211)

Invisible Smoke: Analyzing and Enhancing the Security of Smoke Detectors Under Intentional Electromagnetic Interference. [PDF]

Sensors (Basel)
Liu S, Liu K, Yan C, Pan K, Ji X, Xu W.
europepmc   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Ginsenoside Rg1 Alleviates Chronic Obstructive Pulmonary Disease Partially Through Regulating ABCB1-Mediated Mitochondrial Dysfunction. [PDF]

J Biochem Mol Toxicol
Xu W, Ye J, Dong K, Cao Z, Zhu Y, Li L, Huang B.   +6 more
europepmc   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Mogroside V regulates autophagy through AMPK/mTOR pathway to ameliorate cigarette smoke-induced acute lung injury. [PDF]

J Cardiothorac Surg
Wang W, Wang W, Liu X, Shi W.
europepmc   +1 more source

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

Advanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu, Xi Li, Wenxuan He, Fenglin Li, Qican Ou, Yao Liu, Jiang Lei, Yanzi Bao, Huaxin Huang, Wei Feng, Yuanguang Tang, Xiaohui Qiu, Lu Gan, Yuefei Shen, Jin Wang, Yousheng Xiao   +15 more
wiley   +1 more source

A Multi-Stage Computer Vision Framework for Real-Time Fire Detection in Low-Light Multi-Camera Environments. [PDF]

Sensors (Basel)
Taş R.
europepmc   +1 more source

Architecting Anisotropic Force‐Responsive Bidirectional High‐Contrast Three‐Color Fluorescence Switches via Effective Molecular Modulation for High‐Security Information Storage

Advanced Science, EarlyView.
Synergistically integrating substituent variation and positional isomerism in molecular engineering affords 13 rare tricolored mechanofluorochromic luminogens, and 3 exceedingly scarce force‐triggered bidirectional high‐contrast three‐color fluorescence switches are screened out via a three‐step protocol.
Yijie Zou, Zhao Chen, Shuang Li, Dian‐dian Deng, Hui‐juan Zhang, Hai‐feng He, Ya Yin, Zujin Zhao   +7 more
wiley   +1 more source

Family based screening and smoking cessation for COPD detection: Hybrid cross-sectional and single-arm, multicenter intervention study. [PDF]

Tob Induc Dis
Rábade-Castedo C, Rodríguez-García C, Lado-Argibay P, Fernández-Morón G, Vázquez-Millán PS, Fernández-Moreno JA, Pereiro-Brea T, Buján-Garmendia S, Carbajales-Bouzón MC, Breijo-Pena MJ, Canosa-Santos E, Varela-Sanda T, Fernández-Fernández E, Vela-Flórez L, Blanco-Rodríguez JR, Dablanca-Pallares M, Mascareñas-Pazos P, Toubes-Navarro ME, Zamarrón-Sanz C, Valdés-Cuadrado L.   +19 more
europepmc   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source