Results 1 to 10 of about 69,543 (176)

A novel large animal model of smoke inhalation-induced acute respiratory distress syndrome [PDF]

Respiratory Research, 2021
Background Acute respiratory distress syndrome (ARDS) is multifactorial and can result from sepsis, trauma, or pneumonia, amongst other primary pathologies.
Premila D. Leiphrakpam, Hannah R. Weber, Andrea McCain, Roser Romaguera Matas, Ernesto Martinez Duarte, Keely L. Buesing   +5 more
doaj   +2 more sources

Emerging therapies for smoke inhalation injury: a review [PDF]

Journal of Translational Medicine, 2020
Background Smoke inhalation injury increases overall burn mortality by up to 20 times. Current therapy remains supportive with a failure to identify an optimal or targeted treatment protocol for smoke inhalation injury.
Alexandra Mercel, Nick D. Tsihlis, Rob Maile, Melina R. Kibbe   +3 more
doaj   +2 more sources

Exercise-induced myocardial ischemia presenting as exercise intolerance after carbon monoxide intoxication and smoke inhalation Injury: case report [PDF]

BMC Cardiovascular Disorders, 2022
Background Carbon monoxide intoxication and smoke inhalation injury can lead to severe disorders, and the current literature has elaborated on the importance of major cardiopulmonary impairment.
Yu-Mei Wang, Chao-Chun Huang, Kuan-Fu Liu, Chen-Liang Chou, Jen-Ting Lee, Su-Ying Hung, Po-Cheng Hsu   +6 more
doaj   +2 more sources

MicroRNA-155 Participates in Smoke-Inhalation-Induced Acute Lung Injury through Inhibition of SOCS-1 [PDF]

Molecules, 2020
Smoke inhalation causes acute lung injury (ALI), a severe clinical disease with high mortality. Accumulating evidence indicates that microRNA-155 (miR-155) and suppressor of cytokine signaling 1 (SOCS-1), as mediators of inflammatory response, are ...
Yue Zhang, Yifang Xie, Leifang Zhang, Hang Zhao   +3 more
doaj   +2 more sources

Bronchopleural fistula secondary to smoke inhalation injury: a case report [PDF]

Journal of Medical Case Reports
Background Bronchopleural fistula is a rare and severe condition characterized by an abnormal connection between the bronchial tree and pleural space, often leading to significant morbidity and mortality.
Ibrahim Zahid, Roohan Tahir, Aruba Sohail, Brandon J. Hooks   +3 more
doaj   +2 more sources

Colonic oxygen microbubbles augment systemic oxygenation and CO2 removal in a porcine smoke inhalation model of severe hypoxia [PDF]

Intensive Care Medicine Experimental, 2023
Inhalation injury can lead to pulmonary complications resulting in the development of respiratory distress and severe hypoxia. Respiratory distress is one of the major causes of death in critically ill patients with a reported mortality rate of up to 45%.
Paul A. Mountford, Premila D. Leiphrakpam, Hannah R. Weber, Andrea McCain, Robert M. Scribner, Robert T. Scribner, Ernesto M. Duarte, Jie Chen, Dragana Noe, Mark A. Borden, Keely L. Buesing   +10 more
doaj   +2 more sources

Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice [PDF]

Journal of Neuroinflammation, 2023
Smoke from wildland fires has been shown to produce neuroinflammation in preclinical models, characterized by neural infiltrations of neutrophils and monocytes, as well as altered neurovascular endothelial phenotypes.
David Scieszka, Yan Jin, Shahani Noor, Ed Barr, Marcus Garcia, Jessica Begay, Guy Herbert, Russell P. Hunter, Kiran Bhaskar, Rahul Kumar, Rama Gullapalli, Alicia Bolt, Mark A. McCormick, Barry Bleske, Haiwei Gu, Matthew J. Campen   +15 more
doaj   +2 more sources

A next-generation system for smoke inhalation integrated with a breathing lung-on-chip to model human lung responses to cigarette exposure [PDF]

Scientific Reports
Continuous exposure to cigarette smoke (CS) significantly contributes to the development and progression of chronic obstructive pulmonary disease (COPD) and lung cancer.
Arunima Sengupta, Saskia Schmid, Noémie Grangier, Aurélien Dorn, Marco Hebestreit, Andreas Hugi, Kristína Žajdlíková, Anja Herbst, Paula Losada-Oliva, Heidi Ortolf-Wahl, Philippe Krebs, Janick D. Stucki, Vera van der Velpen, Jesus Perez-Gil, Tobias Krebs, Nina Hobi, Olivier T. Guenat   +16 more
doaj   +2 more sources

Impact of cigarette smoke and aerobic physical training on histological and molecular markers of prostate health in rats [PDF]

Brazilian Journal of Medical and Biological Research, 2020
Recent evidence suggests that aerobic physical training may attenuate the deleterious effects of cancer risk factors, including smoking. We investigated the effects of cigarette smoke inhalation and aerobic physical training on the expression of steroid ...
A.S.C. Veras, D.B. Baptista, N.J. dos Santos, H.H.A. Thorpe, P.M. Seraphim, A.R. Florido Neto, G.R. Teixeira   +6 more
doaj   +1 more source

Inhaled D-Limonene minimizes acute lung injury and reduces oxidative stress induced by smoke in rats

Phytomedicine Plus, 2022
Background: Despite some advances in the discovery of novel therapies, smoke inhalation injury remains a difficult to treat critical health issue due to its physiopathological complexity.
Hericalizandra Santa Rosa Santana, Fernanda Oliveira de Carvalho, Danillo Menezes dos Santos, Eric Aian Pereira da Silva, Érika Ramos Silva, Saravanan Shanmugam, Luana Heimfarth, Paula Santos Nunes, Ana Mara de Oliveira e Silva, Adriano Antunes de Souza Araújo, Ricardo Luiz Cavalcanti de Albuquerque, Márcio Roberto Viana dos Santos   +11 more
doaj   +1 more source