Results 121 to 130 of about 263 (200)

A Novel Nogo‐A Receptor Antagonist Peptide Impedes Alzheimer's Disease Pathology by Nogo‐A/NgR/ROCK Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
NAP2, a NgR1 antagonist peptide, improved cognition in APP/PS1 mice, reduced Aβ plaques and tau hyperphosphorylation, increased dendritic spine density, and alleviated mitochondrial damage, acting through inhibition of the Nogo‐A/NgR/ROCK pathway, highlighting its therapeutic potential for Alzheimer's disease.
Zheng Zhang, Huimin Tan, Fang Shi, Jiajia Dai, Weilong Ding, Junliang Li, Yuke Wang, Rui Yang, Xinke Xu, Cheng Chen, Fei Xiao, Li‐an Huang, Xiaoyan Liu, Rui Liao, Li Yan   +14 more
wiley   +1 more source

Patophysiology of the lung inhalation injuries [PDF]

Vojnosanitetski Pregled, 2007
Vulović Tatjana, Đorđević Gordana
doaj   +1 more source

From scarring to healing: Emerging regenerative therapies for pulmonary fibrosis using MSCs and exosomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
MSCs exert anti‐inflammatory, anti‐fibrotic and regenerative effects in pulmonary fibrosis. MSC‐derived exosomes reproduce many therapeutic benefits of parental MSCs. Preconditioning and genetic modification improve MSC therapeutic performance. Current preclinical and clinical evidence supports the translational potential of MSC‐based therapies ...
Hajar Nasiri, Farbod Khosravi, Fatemeh Eskandari, Tahereh Manoochehrabadi, Ali Samadikuchaksaraei, Ehsan Lotfi, Jila Majidi, Fatemeh Rafati, Zeynab Ghorbani   +8 more
wiley   +1 more source

The Effects of High‐ and Moderate‐Intensity Exercise on Epithelial Integrity Markers and Inflammatory Responses in Healthy Young Men

European Journal of Sport Science, Volume 26, Issue 8, August 2026.
ABSTRACT The effects of exercise intensity on airway epithelial integrity markers and inflammatory responses remain unknown. Therefore, we investigated the effects of high‐ and moderate‐intensity exercise on airway epithelial integrity markers (club cell protein 16 [CC16], surfactant protein D [SP‐D], and the CC16/SP‐D ratio), along with systemic ...
Saeid Nikoukheslat, Hadi Pourmanaf, Vahid Sari‐Sarraf, Ramin Amirsasan, Dean E. Mills   +4 more
wiley   +1 more source

Comparison of the Relationships Between Body Size and Cardiorespiratory Fitness With High Frequency Head‐Motion Contamination in fMRI

Human Brain Mapping, Volume 47, Issue 11, 01 August 2026.
We examine, in older adults, whether cardiorespiratory fitness and body size associate with head motion related signals that introduce noise to brain scans. Body size was most strongly related to head motion, and following an exercise intervention, only reduced body size was related to reduced head motion.
Marco Pipoly, Hayley Chappell, Lyndsey E. DuBose, Bryan Madero, Adriana Rivera‐Dompenciel, Matthew Sodoma, Chris Oehler, Will Daniels, Kelsey Baller, Jenna Springer, Matthew Armstrong, Virginia Nuckols, Vincent Magnotta, Jeffrey Long, Gary L. Pierce, Michelle W. Voss   +15 more
wiley   +1 more source

Effects of Lavender Inhalation Aromatherapy on Depression in Individuals Undergoing Drug Treatment for Substance Dependence: A Randomized Clinical Trial

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Depression is common among individuals undergoing treatment for substance dependence and may adversely affect outcomes. This study determined the short‐term effect of lavender aromatherapy on depressive symptoms in individuals undergoing treatment for substance dependence.
Zahra Sotoudehnia Korrani, Amir Musarezaie, Mahtab Naraghirad, Meysam Rezazadeh   +3 more
wiley   +1 more source

ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu, Sheng Zhang, Jinxi He, Bo Ma, Xuyang Song, Rui Qiu, Bo Yu   +6 more
wiley   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source