Results 181 to 190 of about 31,523 (275)

A meta‐analysis of sexual orientation inequities in substance use among youth

open access: yesAddiction, Volume 121, Issue 5, Page 1048-1063, May 2026.
Abstract Background and Aims Sexual minority youth report significantly higher rates of substance use than heterosexual youth, yet a comprehensive and systematic evaluation and synthesis of the magnitude of this inequity has not been conducted. The purpose of this study was to conduct a meta‐analysis to assess the magnitude of overall inequities in ...
Ethan H. Mereish   +4 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

Association Between Volatile Organic Compound Metabolites in Urine and Adult Lung Function: Evidence From NHANES 2011–2012

open access: yesThe Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
Using BKMR, we observed the joint effects of 16 UM‐VOCs on adult lung function decline. Urinary AMCC and CYMA were identified as the most important contributors to the decline in FEV1/FVC and FeNO, respectively. Tobacco smoke may be the main source of VOCs exposure.
Qian Liu   +6 more
wiley   +1 more source

Systematic Review and Meta‐Analysis of the Prevalence of Substance Use Among Adolescents in South Africa

open access: yesDrug and Alcohol Review, Volume 45, Issue 4, May 2026.
ABSTRACT Introduction Substance use among young people is a growing public health concern in South Africa (SA), with implications for short‐ and long‐term mental health, education and development. A lack of use data is among several challenges impeding progress to support young people.
Carrie Brooke‐Sumner   +12 more
wiley   +1 more source

Higher THC Concentration Medicinal Cannabis Products Efficacy and Safety Considerations: A Rapid Review

open access: yesDrug and Alcohol Review, Volume 45, Issue 4, May 2026.
ABSTRACT Issues Higher delta‐9‐tetrahydrocannabinol (THC) concentration medicinal cannabis products are characterised by a higher THC and minimal cannabidiol (CBD) content. This rapid review aims to systematically summarise and evaluate the available evidence regarding the efficacy and safety of higher THC potency medicinal cannabis products relevant ...
Myfanwy Graham   +3 more
wiley   +1 more source

Exploring Age and Sex Differences in the Use of Cannabis Vaping Products: Results From the Canadian Cannabis Survey 2020–2023

open access: yesDrug and Alcohol Review, Volume 45, Issue 4, May 2026.
ABSTRACT Introduction Use of cannabis vaping products has been increasing in Canada. This study examined the prevalence and patterns of use of cannabis vaping products, including higher‐risk use, by sex and age. Methods Data were from four cycles of the Canadian Cannabis Survey, an annual web‐based survey of people aged ≥ 16 years in Canada.
Fathima Fataar   +3 more
wiley   +1 more source

Influence of low‐dose dopamine on exercise in fibrosing interstitial lung disease

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2682-2695, 1 May 2026.
ABSTRACT Fibrotic interstitial lung disease (FILD) is associated with dyspnoea and exercise intolerance. In other cardiorespiratory conditions, heightened carotid body (CB) chemoreflex sensitivity is associated with reduced exercise capacity. We tested the hypothesis that CB chemoreflex inhibition would improve exercise endurance time (EET) and reduce ...
Charlotte Chen   +6 more
wiley   +1 more source

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